Author: Mokhtar

  • Psoriatic Arthritis of the Knees

    Psoriatic Arthritis of the Knees

    Psoriatic Arthritis of the Knees: Symptoms, Causes, and Treatment

    Psoriatic arthritis is a chronic autoimmune disease that causes inflammation in the joints and skin. It is a type of arthritis that affects people who have psoriasis, a skin condition that causes red, scaly patches on the skin. Psoriatic arthritis can affect any joint in the body, including the knees, and can cause pain, stiffness, and swelling.

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    Psoriatic arthritis of the knees can be particularly debilitating, as it can affect a person’s ability to walk, climb stairs, and perform everyday activities. The symptoms of psoriatic arthritis in the knees can vary from person to person, but common symptoms include pain, swelling, stiffness, and difficulty moving the knee joint. It is important to diagnose and treat psoriatic arthritis of the knees early on to prevent further joint damage and improve quality of life.

    Key Takeaways

    • Psoriatic arthritis is a chronic autoimmune disease that affects people who have psoriasis.
    • Psoriatic arthritis of the knees can cause pain, swelling, stiffness, and difficulty moving the knee joint.
    • Early diagnosis and treatment of psoriatic arthritis of the knees is important to prevent further joint damage and improve quality of life.

    Understanding Psoriatic Arthritis

    Psoriatic arthritis (PsA) is a chronic, inflammatory arthritis that affects people who have psoriasis. Psoriasis is a skin condition that causes skin cells to build up and form plaques—dry, itchy patches of skin. PsA can cause pain, stiffness, and swelling in the joints, including the knees.

    PsA is an autoimmune disease, which means that the immune system attacks healthy cells in the body. In PsA, the immune system attacks the joints, causing inflammation and damage. Over time, this can lead to joint deformities and disability.

    PsA is a chronic condition, which means that it lasts for a long time—often for the rest of a person’s life. However, with the right treatment, many people with PsA can lead full, active lives.

    The goal of treatment for PsA is to reduce inflammation, relieve pain, and prevent joint damage. There are several types of medications that are used to treat PsA, including disease-modifying antirheumatic drugs (DMARDs), nonsteroidal anti-inflammatory drugs (NSAIDs), and biologics.

    DMARDs are a type of medication that can slow down the progression of joint damage in PsA. They work by suppressing the immune system, which reduces inflammation in the joints. Some common DMARDs used to treat PsA include methotrexate, sulfasalazine, and leflunomide.

    NSAIDs are a type of pain reliever that can help reduce inflammation and relieve pain in the joints. They are available over-the-counter or by prescription, and include drugs like ibuprofen and naproxen.

    Biologics are a type of medication that are designed to target specific parts of the immune system that are involved in inflammation. They are given by injection or infusion, and include drugs like etanercept, adalimumab, and infliximab.

    In addition to medication, there are other treatments that can help manage the symptoms of PsA. Physical therapy and exercise can help improve joint mobility and reduce pain. Lifestyle changes, such as maintaining a healthy weight and avoiding smoking, can also help reduce inflammation and improve overall health.

    Overall, PsA is a chronic condition that can cause pain, stiffness, and swelling in the joints, including the knees. However, with the right treatment, many people with PsA can lead full, active lives.

    Psoriatic Arthritis and the Knees

    Psoriatic arthritis (PsA) is a type of inflammatory arthritis that can affect many joints in the body, including the knees. PsA is a chronic autoimmune disease that can cause joint damage, leading to stiffness, swelling, and pain. It can also cause tendons and ligaments to become inflamed, making it difficult to move the affected joints.

    When PsA affects the knees, it can cause significant discomfort and make it difficult to walk. Knee pain is a common symptom of PsA, and it can be accompanied by stiffness and swelling. In some cases, PsA flares can cause such severe pain that walking becomes nearly impossible.

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    PsA can cause joint damage over time, leading to permanent disability. It’s important to seek medical treatment as soon as possible to prevent joint damage and manage symptoms. Treatment options for PsA of the knees may include nonsteroidal anti-inflammatory drugs (NSAIDs) to reduce pain and inflammation, disease-modifying antirheumatic drugs (DMARDs) to slow the progression of the disease, and biologic medications to target specific parts of the immune system.

    In addition to medical treatment, there are also lifestyle changes that can help manage symptoms of PsA and improve overall joint health. Maintaining a healthy weight, staying physically active, and avoiding activities that put excessive stress on the knees can all help reduce symptoms and prevent further joint damage.

    In conclusion, PsA can affect the knees and cause significant pain, stiffness, and swelling. It’s important to seek medical treatment and make lifestyle changes to manage symptoms and prevent joint damage. With proper treatment and care, it’s possible to live a full and active life with PsA.

    Symptoms of Psoriatic Arthritis in the Knees

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    Psoriatic arthritis is a chronic autoimmune disease that affects millions of people worldwide. It is a type of arthritis that can cause inflammation and pain in the joints, including the knees. Here are some of the common symptoms of psoriatic arthritis in the knees:

    • Pain: Joint pain is one of the most common symptoms of psoriatic arthritis in the knees. The pain can be mild to severe and can be felt in one or both knees. It can also be felt in other joints in the body, such as the hips, ankles, and wrists.
    • Swelling: Swelling and inflammation are also common symptoms of psoriatic arthritis in the knees. The swelling can be mild or severe and can make it difficult to move the knee joint.
    • Stiffness: Stiffness in the knee joint is another common symptom of psoriatic arthritis. The stiffness can be worse in the morning or after periods of inactivity. It can also be caused by inflammation in the knee joint.
    • Flares: Psoriatic arthritis can cause flares, which are periods of increased joint pain, swelling, and stiffness. Flares can be triggered by stress, illness, or other factors.
    • Fatigue: Fatigue is a common symptom of psoriatic arthritis. It can be caused by the inflammation in the body and the stress of living with a chronic condition.
    • Tenderness: Tenderness in the knee joint is another symptom of psoriatic arthritis. The knee joint may be tender to the touch, and it may be painful to put weight on the affected leg.

    If you are experiencing any of these symptoms, it is important to talk to your doctor. Your doctor can help you manage your symptoms and develop a treatment plan that works for you.

    Diagnosis of Psoriatic Arthritis

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    If you suspect that you may have psoriatic arthritis, it is important to see a doctor who specializes in rheumatology. A rheumatologist can diagnose psoriatic arthritis based on your medical history, physical exam, and certain tests.

    During the physical exam, the doctor will look for signs of psoriasis, such as red, scaly patches of skin. They will also examine your joints for signs of inflammation, such as swelling, warmth, and tenderness.

    To confirm a diagnosis of psoriatic arthritis, the doctor may order certain tests, including blood tests, X-rays, MRI scans, and ultrasounds. These tests can help the doctor determine the extent of joint damage and rule out other conditions that can cause similar symptoms.

    One blood test that may be ordered is the rheumatoid factor (RF) test. This test can help distinguish between psoriatic arthritis and rheumatoid arthritis. While RF is often present in the blood of people with rheumatoid arthritis, it is not typically present in people with psoriatic arthritis.

    An X-ray can show joint damage and bone loss, while an MRI can provide more detailed images of the joints and surrounding tissues. An ultrasound can also be used to visualize inflammation in the joints.

    Overall, the diagnosis of psoriatic arthritis can be challenging because it shares many symptoms with other types of arthritis. However, with the help of a rheumatologist and various diagnostic tests, a diagnosis can be made and appropriate treatment can be started.

    02 Tables

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    Tables can be a useful way to display information about Psoriatic arthritis of the knees. Here are some examples of information that can be displayed in tables:

    • Symptoms: Common symptoms of Psoriatic arthritis of the knees include pain, stiffness, swelling, and warmth in the joint. Other symptoms may include fatigue, nail changes, and eye inflammation.
    • Diagnosis: A diagnosis of Psoriatic arthritis of the knees may involve a physical exam, blood tests, imaging tests (such as X-rays or MRI), and joint fluid tests.
    • Treatment: Treatment for Psoriatic arthritis of the knees may involve medications (such as nonsteroidal anti-inflammatory drugs, disease-modifying antirheumatic drugs, or biologic agents), physical therapy, and surgery (in severe cases).
    • Prevention: There is no known way to prevent Psoriatic arthritis of the knees, but maintaining a healthy weight, avoiding smoking, and managing stress may help reduce the risk of developing the condition.

    Tables can also be used to compare different treatment options for Psoriatic arthritis of the knees, such as the benefits and risks of different medications. It is important to discuss treatment options with a healthcare provider to determine the best course of action for each individual case.

    In addition to tables, bullet points can be used to summarize key information about Psoriatic arthritis of the knees. Bold text can be used to highlight important terms or concepts, making it easier for readers to quickly scan the information and find what they are looking for.

    Overall, tables and other formatting tools can be a helpful way to present information about Psoriatic arthritis of the knees in a clear and organized manner.

    Causes and Risk Factors

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    Psoriatic arthritis (PsA) is a type of inflammatory arthritis that can develop in people who have psoriasis. The exact cause of PsA is not yet known, but research suggests that it may result from a combination of genetic, environmental, and immune system factors.

    One of the main risk factors for developing PsA is having psoriasis, a chronic autoimmune skin disorder that causes red patches of skin topped with silvery scales. In fact, up to 30% of people with psoriasis may develop PsA. The severity of psoriasis does not necessarily predict the development of PsA.

    Age is another risk factor for developing PsA, with most people being diagnosed between the ages of 30 and 50. However, PsA can occur at any age, including in children.

    Family history is also a significant risk factor for PsA. People with a family history of PsA or psoriasis are more likely to develop the condition themselves.

    Certain environmental factors, such as smoking, obesity, and stress, may also increase the risk of developing PsA. Infections, particularly those caused by streptococcal bacteria, may also trigger the onset of PsA in some people.

    PsA can also be associated with nail disease, such as nail pitting or separation from the nail bed. In some cases, PsA can also be associated with rheumatoid arthritis.

    In conclusion, the exact cause of PsA is not yet known, but research suggests that it may result from a combination of genetic, environmental, and immune system factors. Having psoriasis, a family history of PsA or psoriasis, and certain environmental factors may increase the risk of developing PsA.

    Effects on Other Body Parts

    Psoriatic arthritis is a chronic inflammatory disease that affects not only the joints but also other parts of the body. In addition to joint pain, swelling, and stiffness, psoriatic arthritis can cause a range of symptoms in different body parts.

    Skin and Nails

    Psoriasis, a skin condition characterized by red, scaly patches on the skin, is often associated with psoriatic arthritis. In fact, up to 30% of people with psoriasis develop psoriatic arthritis. In addition to skin patches, psoriasis can also cause nail changes such as pitting, ridges, and discoloration.

    Hands, Elbows, Feet, and Fingers

    Psoriatic arthritis can affect any joint in the body, but it most commonly affects the joints of the hands, feet, and fingers. This can cause pain, swelling, and stiffness in these joints, making it difficult to perform daily activities.

    Spine

    Psoriatic arthritis can also affect the spine, causing pain and stiffness in the neck and lower back. This can make it difficult to bend, twist, or move the spine.

    Eyes

    Psoriatic arthritis can cause eye inflammation, a condition known as uveitis. Uveitis can cause eye redness, pain, and sensitivity to light. It is important to seek medical attention if you experience any of these symptoms.

    Lungs

    In rare cases, psoriatic arthritis can cause inflammation in the lungs, leading to shortness of breath and chest pain. This is known as psoriatic arthritis-associated interstitial lung disease.

    Toes

    Psoriatic arthritis can also affect the toes, causing pain and swelling in the joints of the toes. This can make it difficult to walk or wear shoes.

    In conclusion, psoriatic arthritis can affect various body parts, causing a range of symptoms. It is important to seek medical attention if you experience any of these symptoms to receive an accurate diagnosis and appropriate treatment.

    Treatment and Management

    When it comes to psoriatic arthritis of the knees, treatment and management are essential for reducing pain and inflammation, preventing joint damage, and improving overall quality of life.

    There are several treatment options available, including medications such as nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, corticosteroid injections, disease-modifying antirheumatic drugs (DMARDs) like methotrexate, and biologics. The type of medication prescribed will depend on the severity of the disease and the patient’s overall health.

    In addition to medication, managing pain and inflammation can be achieved through physical therapy, exercise, and lifestyle changes such as maintaining a healthy weight and avoiding triggers that worsen symptoms. Surgery may also be an option in severe cases where joint damage is significant.

    It’s important to note that while there is no cure for psoriatic arthritis, achieving remission is possible with the right treatment plan. Regular checkups with a healthcare provider can help monitor the disease and adjust treatment as needed.

    Overall, by working closely with healthcare providers and following a comprehensive treatment plan, individuals with psoriatic arthritis of the knees can effectively manage symptoms and improve their quality of life.

    Living with Psoriatic Arthritis

    Living with psoriatic arthritis can be challenging, but there are ways to manage symptoms and improve quality of life. We have compiled some tips and strategies to help those with psoriatic arthritis.

    Exercise

    Exercise is important for maintaining joint flexibility, muscle strength, and overall health. Low-impact exercises such as swimming, cycling, and yoga can be beneficial for those with psoriatic arthritis. It is important to consult with a healthcare provider before starting any new exercise program.

    Damage

    Psoriatic arthritis can cause joint damage if left untreated. It is important to work with a healthcare provider to develop a treatment plan to manage symptoms and prevent joint damage.

    Diarrhea

    Some medications used to treat psoriatic arthritis can cause diarrhea. It is important to discuss any side effects with a healthcare provider and to follow their recommendations for managing symptoms.

    Heart

    Psoriatic arthritis has been linked to an increased risk of heart disease. It is important to manage cardiovascular risk factors such as high blood pressure, high cholesterol, and smoking.

    Skin Cells and Plaques

    Psoriasis is a chronic autoimmune skin disorder that causes skin cells to build up and form plaques. Psoriatic arthritis is a type of inflammatory arthritis that develops in people who have psoriasis. It is important to manage symptoms of psoriasis and psoriatic arthritis to prevent joint damage and other complications.

    Depression

    Living with a chronic condition such as psoriatic arthritis can be difficult and can lead to depression. It is important to seek support from family, friends, and healthcare providers to manage symptoms of depression.

    Metabolic Syndrome and Diabetes

    Psoriatic arthritis has been linked to an increased risk of metabolic syndrome and diabetes. It is important to manage these conditions with a healthy diet, regular exercise, and medication as prescribed by a healthcare provider.

    Family Member

    Psoriatic arthritis can run in families. It is important to inform family members of the condition and to encourage them to seek medical attention if they experience symptoms.

    Healthcare Provider

    Working with a healthcare provider is essential for managing psoriatic arthritis. It is important to communicate any symptoms or side effects of medication to a healthcare provider and to follow their recommendations for managing the condition.

    Back Pain

    Psoriatic arthritis can cause back pain and stiffness. It is important to work with a healthcare provider to develop a treatment plan to manage symptoms and prevent joint damage.

    Bloating

    Some medications used to treat psoriatic arthritis can cause bloating. It is important to discuss any side effects with a healthcare provider and to follow their recommendations for managing symptoms.

    Frequently Asked Questions

    What are the early warning signs of psoriatic arthritis?

    Psoriatic arthritis is a type of arthritis that affects some people who have psoriasis. The symptoms of psoriatic arthritis can vary, but some early warning signs include joint pain, stiffness, and swelling. Other common symptoms include fatigue, nail changes, and skin rashes. If you experience any of these symptoms, it is important to talk to your doctor.

    What does psoriatic arthritis in knees feel like?

    Psoriatic arthritis in knees can cause pain, swelling, and stiffness in the joints. This can make it difficult to walk, climb stairs, or stand for long periods of time. Some people with psoriatic arthritis in knees may also experience redness and warmth in the affected joint.

    Does psoriatic arthritis hurt all the time?

    No, psoriatic arthritis does not always hurt all the time. Some people with psoriatic arthritis may experience periods of time when their symptoms are mild or absent, while others may have ongoing pain and discomfort. It is important to work with your doctor to find a treatment plan that works for you.

    Is walking good for psoriatic arthritis?

    Yes, walking can be good for psoriatic arthritis. Exercise can help improve joint flexibility, reduce pain and stiffness, and improve overall health and well-being. However, it is important to talk to your doctor before starting any exercise program to make sure it is safe for you.

    What are some common treatments for psoriatic arthritis?

    There are several treatments available for psoriatic arthritis, including nonsteroidal anti-inflammatory drugs (NSAIDs), disease-modifying antirheumatic drugs (DMARDs), and biologic therapies. Your doctor may also recommend physical therapy, occupational therapy, or other treatments depending on your symptoms and the severity of your condition.

    What does a psoriatic arthritis flare feel like?

    A psoriatic arthritis flare can cause sudden and severe joint pain, swelling, and stiffness. This can make it difficult to move or perform everyday tasks. Flares can last for several days or weeks and may be triggered by stress, illness, or other factors. If you experience a flare, it is important to talk to your doctor about adjusting your treatment plan.

  • Spine Research Fellowship – Gillette Children’s Hospital (2024-2025)

    The Gillette Children’s Hospital Pediatric Orthopedic Research Fellowship is a fully funded, one-year fellowship program intended for medical students and recent medical school graduates who are interested in pursuing a career in orthopedic surgery. Fellows will participate in clinically informed pediatric orthopedic research and gain experience in all facets of research activities, including design, implementation and dissemination. In addition to actively participating in research, fellows will have the opportunity to attend daily didactic educational sessions in the Department of Pediatric Orthopedic Surgery, observe the clinical and surgical management of children with complex spine conditions, and receive mentorship from our clinical and research team.

    To be considered for this opportunity, please submit your CV, transcript (can be unofficial) and motivation letter with your application with the points below:

    1. Experience with research, scientific writing and/or literature research.
    2. Your goals and expectations for this one-year research fellowship at Gillette Children’s.
    3. How this one-year research grant can help you realize your ultimate career plans in medicine.

    compensation and benefits

    The hourly rate for this opportunity is $22/hour. Hourly wages are only part of the employee compensation package. Gillette supports career development and offers a competitive benefits package, including a retirement savings plan, tuition and degree reimbursement, paid time off and health and wellness benefits.

    Significant challenges

    • Make significant contributions to multiple research projects, including designing the research protocol, obtaining human subject approvals, collaboration and communication among the research team, and involvement in data analysis.
    • Lead dissemination efforts, resulting in submission of abstracts for presentation at a scientific conference and/or submission of peer-reviewed manuscripts for publication.
    • Manage timelines for ongoing projects while maintaining a weekly schedule consisting of team conferences, clinics, and mentorship meetings.
    • Meet internal and external deadlines to ensure consistent progress on ongoing projects, including research activities, presentations, manuscripts, grant proposal development, and other collaborative work.

    Key Job Responsibilities

    The fellow will be involved in a variety of research projects designed to answer questions and solve problems in pediatric spine, patient safety, and healthcare quality and value, as well as medical economics. Completed projects will be submitted for publication in high-quality journals and presentations at regional, national and international conferences.

    Qualifications

    Required (for Fellowship start date on or about July 1, 2024):

    • Fellows have completed their third year of medical school. Exceptional candidates who have completed their second year of medical school are also eligible.
    • Fellows are in good academic standing and have an interest in pursuing a career in orthopedics or spine surgery.

    Preference:

    • Fellows have previous experience in scholarly writing, literature review, and/or research experience.

    Gillette Children’s is committed to recruiting and retaining a diverse team because we know that the diverse experiences of our employees make Gillette a stronger and better organization. We strive to create an equitable and inclusive environment where all patients, families and staff are welcomed and valued. We believe that diverse perspectives and identities promote excellence, improve patient care and are essential for Gillette to fulfill its mission. Our team members work together to help patients of all backgrounds and abilities reach their full potential.

    Gillette Children’s is an equal opportunity employer and will not discriminate against any employee or applicant for employment because of an individual’s race, color, creed, sex, religion, national origin, age, disability, marital status, familial status, genetic information, status with regard to government assistance, sexual orientation or gender identity, military status, or any other class protected by federal, state, or local law.

    Gillette Children’s is a global beacon of care for patients with brain, bone and movement disorders that begin in childhood. Our research, treatment and supportive technologies empower every child to live a full life defined by their dreams, not their diagnoses.

    For more information about working at Gillette Children’s, visit https://www.gillettechildrens.org/careers.

    Gillette Children’s participates in the U.S. Department of Homeland Security (DHS) E-Verify program, an Internet-based employment eligibility verification system administered by U.S. Citizenship and Immigration Services. If E-Verify cannot confirm that you are authorized to work, Gillette will provide you with written instructions and the option to contact DHS or the Social Security Administration (SSA) to resolve the issue before Gillette takes further action undertakes. For more information about e-verify, visit https://www.e-verify.gov/.

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  • Rheumatoid Arthritis

    Rheumatoid Arthritis

    Rheumatoid Arthritis: Causes, Symptoms, and Treatment Options

    Rheumatoid arthritis is a chronic autoimmune disorder that affects millions of people worldwide. It is a type of arthritis that occurs when the immune system attacks the body’s own tissues, particularly the joints. This leads to inflammation and pain, which can be debilitating and affect the quality of life of those who suffer from the condition.

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    Understanding Rheumatoid Arthritis is important in order to manage the symptoms and improve the quality of life of those who suffer from it. It is important to recognize the symptoms early on, as early diagnosis and treatment can help prevent further joint damage and complications. There are a variety of treatment options available, including medications, physical therapy, and surgery, which can help manage the symptoms and improve joint function. In this article, we will explore the causes, symptoms, diagnosis, and treatment options for Rheumatoid Arthritis.

    Key Takeaways

    • Rheumatoid arthritis is a chronic autoimmune disorder that affects the joints and can be debilitating.
    • Early diagnosis and treatment can help prevent further joint damage and complications.
    • Treatment options include medications, physical therapy, and surgery.

    Understanding Rheumatoid Arthritis

    Rheumatoid arthritis (RA) is a chronic autoimmune disorder that affects the joints, causing pain, stiffness, and swelling. It is a systemic disease, which means it can affect other parts of the body as well, such as the eyes, skin, lungs, and blood vessels.

    The exact cause of RA is still unknown, but it is believed to be caused by a combination of genetic and environmental factors. In RA, the immune system mistakenly attacks the synovial membrane, which is the lining that surrounds the joints. This results in inflammation, which can cause damage to the joints over time.

    RA is a chronic disease, which means that it can last for a long time and may require ongoing treatment. However, with early diagnosis and appropriate treatment, it is possible to manage the symptoms of RA and prevent joint damage.

    The symptoms of RA can vary from person to person, but some common symptoms include joint pain, stiffness, and swelling, especially in the hands, feet, and wrists. Other symptoms may include fatigue, fever, and weight loss.

    There is no cure for RA, but there are several treatment options available to manage the symptoms and slow down the progression of the disease. These may include medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs), disease-modifying antirheumatic drugs (DMARDs), and biologic agents. In addition, physical therapy and lifestyle changes, such as regular exercise and a healthy diet, may also be helpful in managing the symptoms of RA.

    In summary, RA is a chronic autoimmune disorder that affects the joints and other parts of the body. It is caused by a combination of genetic and environmental factors, and there is no cure for the disease. However, with early diagnosis and appropriate treatment, it is possible to manage the symptoms of RA and prevent joint damage.

    Symptoms of Rheumatoid Arthritis

    Rheumatoid arthritis (RA) is a chronic autoimmune disease that affects the joints and other parts of the body. The symptoms of RA can vary from person to person, but they generally include joint pain, swelling, and stiffness.

    One of the most common symptoms of RA is joint pain. This pain is often described as a deep ache or a burning sensation, and it can be felt in the joints of the hands, wrists, feet, and ankles. The pain is usually worse in the morning or after periods of inactivity, and it can be accompanied by joint stiffness that lasts for several hours.

    Swelling is another common symptom of RA. The joints affected by RA can become swollen and tender to the touch. This swelling can make it difficult to move the affected joint, and it may also cause the joint to feel warm to the touch.

    Fatigue is also a common symptom of RA. People with RA may feel tired and run down, even if they have had enough sleep. This fatigue can be caused by the inflammation associated with RA, as well as by the stress of dealing with a chronic illness.

    In some cases, people with RA may develop rheumatoid nodules. These are small, firm lumps that can form under the skin, usually around the elbows or fingers. While these nodules are not usually painful, they can be unsightly and may interfere with joint movement.

    Fever is another symptom that can occur in people with RA. This fever is usually low-grade, and it may be accompanied by other flu-like symptoms such as chills and muscle aches.

    Overall, the symptoms of RA can be quite debilitating, and they can have a significant impact on a person’s quality of life. If you are experiencing any of the symptoms associated with RA, it is important to speak with your healthcare provider as soon as possible.

    Causes and Risk Factors

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    Rheumatoid arthritis (RA) is a chronic inflammatory disease that affects the joints, causing pain, stiffness, and swelling. While the exact cause of RA is unknown, there are several factors that are believed to contribute to the development of the disease.

    Genetics

    One of the most significant risk factors for developing RA is genetics. Research has shown that certain genes may make a person more susceptible to the disease. For example, a specific gene called HLA-DRB1 has been linked to an increased risk of developing RA. However, having this gene does not necessarily mean that a person will develop the disease.

    Smoking

    Smoking is another significant risk factor for RA. Studies have shown that smokers are more likely to develop the disease than non-smokers. In addition, smoking can also make the symptoms of RA worse, making it more difficult to manage the disease.

    Sex

    RA is more common in women than men. In fact, women are two to three times more likely to develop the disease than men. The reason for this is not entirely clear, but hormones may play a role. Some researchers believe that estrogen may contribute to the development of RA.

    Other Risk Factors

    In addition to genetics, smoking, and sex, there are several other factors that may increase a person’s risk of developing RA. These include:

    • Age: RA can occur at any age, but it most commonly begins in middle age.
    • Family history: If a member of your family has RA, you may have an increased risk of the disease.
    • Obesity: Being overweight or obese can increase the risk of developing RA, as well as make the symptoms worse.
    • Environmental factors: Exposure to certain environmental factors, such as pollution or toxins, may increase the risk of developing RA.

    Overall, while the exact cause of RA is unknown, there are several factors that are believed to contribute to the development of the disease. By understanding these risk factors, we can take steps to reduce our risk of developing RA and manage the disease more effectively if we do develop it.

    Diagnosis Process

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    When it comes to diagnosing Rheumatoid arthritis (RA), there is no one definitive test or physical finding that can confirm the diagnosis. Instead, doctors use a combination of medical history, physical examination, and laboratory tests to diagnose RA.

    During the medical history, we will ask questions about the patient’s symptoms, family history, and medical history. We will also ask about any medications the patient is taking, as some medications can cause symptoms similar to RA.

    During the physical exam, we will check the patient’s joints for swelling, redness, and warmth. We will also check the patient’s reflexes and muscle strength. The physical exam can help us determine the severity of the patient’s symptoms and which joints are affected.

    Laboratory tests are also an important part of the diagnosis process. We may order a blood test to check for the presence of rheumatoid factor (RF) or anti-cyclic citrullinated peptide (anti-CCP) antibodies. These antibodies are often present in people with RA, but not always. A negative result does not rule out RA.

    Imaging tests, such as X-rays or ultrasound, can also be helpful in diagnosing RA. X-rays can show changes in the joints that are consistent with RA, such as joint erosion or narrowing of the joint space. Ultrasound can show inflammation in the joints and surrounding tissues.

    It is important to note that RA can be difficult to diagnose in the early stages because the disease develops over time, and only a few symptoms may be present. However, with a thorough medical history, physical exam, and laboratory tests, we can diagnose RA and begin treatment to manage symptoms and prevent further joint damage.

    Treatment Options

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    When it comes to treating rheumatoid arthritis, there are a variety of options available. The goal of treatment is to reduce inflammation, relieve pain, prevent joint damage, and improve overall function. Treatment plans are often tailored to each individual and may involve a combination of medications, therapies, and lifestyle changes.

    Medications

    There are several types of medications used to treat rheumatoid arthritis. Nonsteroidal anti-inflammatory drugs (NSAIDs) can help relieve pain and reduce inflammation. Over-the-counter NSAIDs include ibuprofen (Advil, Motrin IB, others) and naproxen sodium (Aleve). Stronger NSAIDs are available by prescription. Side effects may include stomach irritation, heart problems, and kidney damage.

    Disease-modifying antirheumatic drugs (DMARDs) slow the progression of rheumatoid arthritis and can prevent joint damage. Methotrexate (Rheumatrex, Trexall) is a commonly used DMARD. Other DMARDs include hydroxychloroquine (Plaquenil), sulfasalazine (Azulfidine), and leflunomide (Arava).

    Corticosteroids are powerful anti-inflammatory medications that can provide quick relief of symptoms. However, they can have serious side effects if used long-term. Janus kinase (JAK) inhibitors are a newer class of medications that block the action of certain enzymes involved in inflammation.

    Therapies

    Physical and occupational therapy can help improve joint function, reduce pain, and increase range of motion. Splints and braces may also be recommended to support and protect joints.

    Surgery may be necessary in severe cases of rheumatoid arthritis. Joint replacement surgery can help relieve pain and improve function in damaged joints. Synovectomy is a surgical procedure that involves removing the inflamed lining of a joint.

    Lifestyle Changes

    In addition to medications and therapies, making certain lifestyle changes can also help manage rheumatoid arthritis. Maintaining a healthy weight can reduce stress on joints. Regular exercise can help improve joint function and flexibility. Eating a healthy diet rich in fruits, vegetables, and whole grains can also help reduce inflammation.

    Overall, there are a variety of treatment options available for rheumatoid arthritis. Working closely with a healthcare provider to develop a personalized treatment plan can help manage symptoms and improve overall quality of life.

    Managing Rheumatoid Arthritis

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    As individuals with Rheumatoid Arthritis, we know how difficult it can be to manage the symptoms of this chronic condition. However, with proper management, we can improve our quality of life and reduce the impact of RA on our daily activities. Here are some tips for managing Rheumatoid Arthritis:

    Rest

    Rest is crucial for managing RA symptoms. It is important to listen to our body and take breaks when we feel fatigued. This can help reduce inflammation and pain in our joints. We should aim to get enough sleep each night and take naps during the day if needed.

    Exercise

    Exercise is also important for managing RA symptoms. Low-impact exercises such as walking, swimming, and cycling can help improve joint flexibility and reduce inflammation. We should aim to exercise regularly, but it is important to listen to our body and not overdo it. It is also important to speak with our doctor before starting any new exercise routine.

    Diet

    Maintaining a healthy diet can also help manage RA symptoms. We should aim to eat a well-balanced diet that includes plenty of fruits, vegetables, whole grains, and lean protein. Some foods may trigger inflammation, so it is important to identify and avoid these foods. We should also stay hydrated by drinking plenty of water.

    Medications

    There are several medications available that can help manage RA symptoms. Nonsteroidal anti-inflammatory drugs (NSAIDs) can help relieve pain and reduce inflammation. Disease-modifying antirheumatic drugs (DMARDs) can help slow the progression of RA. It is important to speak with our doctor about the best medication options for us.

    Support

    Living with RA can be challenging, and it is important to have a support system. We should reach out to family, friends, and support groups for help and encouragement. We may also benefit from counseling or therapy to help manage the emotional impact of RA.

    By following these tips, we can effectively manage our Rheumatoid Arthritis symptoms and improve our overall quality of life.

    02 Tables

    image 101

    We can use tables to organize information about Rheumatoid arthritis. Here is an example of a table that shows the diagnostic criteria for Rheumatoid arthritis:

    CriteriaDefinition
    Morning stiffnessStiffness in joints lasting at least 1 hour in the morning
    Arthritis of three or more joint areasSwelling or tenderness in at least three joint areas
    Arthritis of hand jointsSwelling or tenderness in the joints of the hand
    Symmetric arthritisSwelling or tenderness in the same joint areas on both sides of the body
    Rheumatoid nodulesFirm lumps under the skin
    Positive rheumatoid factorBlood test positive for rheumatoid factor
    Radiographic changesX-ray evidence of joint erosion or destruction

    Another useful table is the one that shows the severity scale of Rheumatoid arthritis. Here is an example of that table:

    SeverityDefinition
    MildFewer than 3 swollen joints, no systemic symptoms
    Moderate4-10 swollen joints, mild systemic symptoms
    SevereMore than 10 swollen joints, significant systemic symptoms

    It is important to note that these tables are just examples and should not be used as a diagnostic tool. Only a qualified healthcare professional can diagnose Rheumatoid arthritis.

    Effect on Joints and Other Body Parts

    Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that affects various parts of the body. It mainly affects joints, but it can also impact other body parts such as muscles, eyes, and organs.

    RA usually affects both sides of the body symmetrically. It primarily affects small joints, especially those in the hands and feet, but it can also affect larger joints such as the hips, knees, and shoulders.

    RA can cause pain, stiffness, swelling, and tenderness in the joints. In some cases, it can lead to joint deformities such as claw toe, bunions, and hammer toe. RA can also cause joint effusion, which is an abnormal accumulation of fluid inside the joint. This can lead to joint stiffness and difficulty moving or impaired range of motion.

    As RA progresses, it can spread to other joints, including the wrists, ankles, and elbows. It can also affect muscles, causing weakness and fatigue. In some cases, RA can cause osteopenia and stress fractures, making it difficult to walk stairs and up inclined surfaces.

    RA can also affect the eyes, causing dryness, redness, and inflammation. In rare cases, it can lead to scleritis, which is a serious condition that can cause blindness.

    In conclusion, RA can affect various parts of the body, including joints, muscles, eyes, and organs. It primarily affects small joints in the hands and feet but can also impact larger joints such as the hips and knees. RA can cause pain, stiffness, swelling, and tenderness in the joints, as well as joint deformities, joint effusion, and muscle weakness. It is important to seek medical attention if you experience any symptoms of RA.

    Complications and Progression

    Rheumatoid arthritis (RA) is a chronic autoimmune disease that can lead to various complications and progression of symptoms over time.

    One of the most common complications of RA is joint damage, which can result in deformity and loss of function. Joint inflammation, stiffness, and redness are also common symptoms of RA that can affect the quality of life of individuals with the condition.

    In addition to joint-related complications, RA can also lead to systemic inflammation, which can affect other organs and systems in the body. This inflammation can increase the risk of infection and other health issues.

    The severity of RA symptoms can vary from person to person, and some individuals may experience periods of remission where symptoms improve or disappear. However, flares of symptoms can also occur, which can be unpredictable and difficult to manage.

    Treatment for RA can help manage symptoms and slow the progression of joint damage. This can include medications, physical therapy, and lifestyle changes. It is important for individuals with RA to work closely with their healthcare team to develop a personalized treatment plan.

    Overall, RA is a complex condition that requires ongoing management and monitoring. While it can lead to various complications and progression of symptoms, treatment and self-care can help improve function and quality of life for individuals with the condition.

    The Role of Rheumatologists

    As rheumatoid arthritis is a complex autoimmune disorder that affects the joints and other parts of the body, it is essential to seek medical care from a specialist who has extensive knowledge and experience in treating this condition. This is where rheumatologists come in.

    Rheumatologists are medical doctors who specialize in diagnosing and treating musculoskeletal diseases and systemic autoimmune conditions like rheumatoid arthritis. They receive special training in this area, which allows them to provide the best possible care for patients with rheumatoid arthritis.

    The role of rheumatologists is to work with patients to develop an appropriate treatment plan based on their individual needs. They use a variety of diagnostic tools and techniques to determine the severity of the disease and its impact on the patient’s quality of life. This may include X-rays, blood tests, and physical examinations.

    Once a diagnosis has been made, rheumatologists work with patients to develop a treatment plan that may include medication, physical therapy, and lifestyle changes. They also provide ongoing care and support to help patients manage their symptoms and improve their overall health.

    In addition to treating rheumatoid arthritis, rheumatologists may also treat other autoimmune conditions that affect the musculoskeletal system, such as lupus and scleroderma. They may also work with other specialists, such as orthopedic surgeons and physical therapists, to provide comprehensive care for their patients.

    Overall, the role of rheumatologists is essential in the diagnosis and treatment of rheumatoid arthritis. If you are experiencing joint pain, stiffness, or other symptoms associated with this condition, it is important to seek medical care from a rheumatologist to receive the best possible care and support.

    Impact on Specific Populations

    Rheumatoid arthritis (RA) is a chronic inflammatory joint disease that affects people of all ages, genders, and ethnicities. However, certain populations may be more susceptible to developing RA or may experience different outcomes. In this section, we will discuss the impact of RA on specific populations.

    Women

    RA is more common in women than men, with women being three times more likely to develop the disease. Women also tend to develop RA at a younger age than men. The reasons for this gender disparity are not yet fully understood, but hormonal factors may play a role. Women with RA may also experience more severe symptoms and disability than men with RA.

    Men

    Although less common, men can also develop RA. Men with RA may experience a more aggressive disease course and are more likely to develop complications such as heart disease and lung problems. However, men with RA may also have better outcomes in terms of joint damage and disability than women with RA.

    Age

    RA can affect people of all ages, but it most commonly develops in middle age. Older adults with RA may have different treatment considerations due to age-related health concerns and the potential for drug interactions with other medications they may be taking. Children with RA, also known as juvenile idiopathic arthritis, may have different symptoms and treatment options than adults with RA.

    Ethnicity

    RA can affect people of all ethnicities, but some ethnic groups may be more likely to develop the disease or experience more severe symptoms. For example, Native Americans and Alaska Natives have a higher prevalence of RA than other ethnic groups in the United States. African Americans with RA may experience more severe joint damage and disability than other racial or ethnic groups.

    In conclusion, RA can impact people of all ages, genders, and ethnicities, but certain populations may be more susceptible to developing the disease or may experience different outcomes. It is important for healthcare providers to consider these factors when diagnosing and treating RA to ensure the best possible outcomes for all patients.

    Other Related Conditions

    In addition to rheumatoid arthritis (RA), there are other related conditions that individuals with RA may have. These conditions can be comorbidities, which means they occur at the same time as RA, or they can be conditions that mimic RA symptoms.

    Osteoarthritis (OA) is a common type of arthritis that can occur in addition to RA. OA is a degenerative joint disease that affects the cartilage in joints, causing pain, stiffness, and swelling. Unlike RA, which is an autoimmune disease, OA is caused by wear and tear on the joints over time. While RA can affect any joint in the body, OA most commonly affects the knees, hips, and hands.

    Individuals with RA may also have other autoimmune diseases, such as lupus or psoriatic arthritis. Lupus is a chronic autoimmune disease that can affect many parts of the body, including the skin, joints, and organs. Psoriatic arthritis is a type of arthritis that occurs in individuals with psoriasis, a skin condition that causes red, scaly patches on the skin.

    In addition to these conditions, individuals with RA may also be at an increased risk for developing other health problems, such as cardiovascular disease and osteoporosis. This is because chronic inflammation, which is a hallmark of RA, can damage blood vessels and bones over time.

    It is important for individuals with RA to work closely with their healthcare provider to manage their condition and any related health problems. This may involve a combination of medications, lifestyle changes, and other treatments to help reduce inflammation, manage pain, and improve overall health.

    Frequently Asked Questions

    What are the early signs of rheumatoid arthritis?

    The early signs of rheumatoid arthritis (RA) include tender, warm, and swollen joints, joint stiffness that is usually worse in the mornings and after inactivity, fatigue, fever, and loss of appetite. Early RA tends to affect smaller joints first, particularly the joints that attach fingers to hands and toes to feet. If you experience any of these symptoms, it is important to consult a doctor.

    What is the difference between rheumatoid arthritis and other types of arthritis?

    Rheumatoid arthritis is an autoimmune and inflammatory disease, which means that the immune system attacks healthy cells in the body by mistake, causing inflammation in the affected parts of the body. The most common form of arthritis in the United States is osteoarthritis, which is caused by wear and tear on the joints. Other common types of arthritis include gout and fibromyalgia.

    How is rheumatoid arthritis diagnosed?

    Rheumatoid arthritis is diagnosed through a combination of physical exams, medical history, blood tests, and imaging tests. Doctors will look for signs of joint inflammation, such as swelling, tenderness, and warmth, and may order blood tests to check for specific antibodies that are commonly associated with RA.

    What are the most effective medications for treating rheumatoid arthritis?

    There are several types of medications that can be used to treat rheumatoid arthritis, including nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, disease-modifying antirheumatic drugs (DMARDs), and biologic agents. The most effective medications will vary depending on the individual and the severity of their symptoms. It is important to work closely with a doctor to find the best treatment plan.

    What are some dietary recommendations for managing rheumatoid arthritis?

    While there is no specific diet that has been proven to cure rheumatoid arthritis, some dietary changes may help manage symptoms. A diet rich in anti-inflammatory foods, such as fruits, vegetables, whole grains, and omega-3 fatty acids, may help reduce inflammation and pain. It is also important to maintain a healthy weight, as excess weight can put additional stress on joints.

    What are some common struggles experienced by people with rheumatoid arthritis?

    Living with rheumatoid arthritis can be challenging, both physically and emotionally. Some common struggles include chronic pain, fatigue, difficulty performing daily tasks, and feelings of isolation and depression. It is important to seek support from loved ones and healthcare professionals to manage these challenges and maintain a good quality of life.

  • Towards functionally individualised designed footwear recommendation for overuse injury prevention: a scoping review | BMC Sports Science, Medicine and Rehabilitation

    Towards functionally individualised designed footwear recommendation for overuse injury prevention: a scoping review | BMC Sports Science, Medicine and Rehabilitation

    Overview

    Running shoes are often characterised based on their cushioning and motion control functionality. Consequently, we have categorised the literature review results into these sections. We discuss additional FDF that did not fit into the first two sections in a subsequent part, followed by an upper construction segment. In each chapter, we introduce a brief description of the FDF. Next, we present the results of studies, taking covariates into account and analysing BRFs. We further discuss studies that investigated BRFs without considering covariates. Finally, we place our findings in the context of the FDF’s potential to minimise the development of running-related overuse injuries (RRI). We identified 107 articles that met our inclusion criteria (Fig. 4, Supplementary 3 Table 1-12). Most of these articles were published at the start of the twenty-first century and primarily featured data from male runners (Fig. 5). We acknowledge a data gap in running footwear research, which aligns with the female data gap in sport and exercise science [24].

    Fig. 4
    figure 4

    A Scatter plot of the included articles. Articles for each footwear design feature are separated by the number of articles considering covariates (y-axis) and running-related biomechanical risk factors (x-axis). If applicable, covariates for each footwear design feature are reported. According to a recent Delphi study, scatters are scaled to their importance [25]. Larger diameters represent a higher level of importance, and smaller diameters a lower level of importance. White scatters were not reported in the Delphi study and are not scaled

    Fig. 5
    figure 5

    The publication timeline of the included articles, separated by the different footwear design features. Each pie chart represents one study with the fraction of male (dark-grey) and female (light-grey) runners. Pie charts are scaled to the number of runners included in the study. Larger diameters indicate larger sample sizes, and smaller diameters indicate smaller sample sizes

    Cushioning systems

    Cushioned midsoles were one of the first FDF introduced to modern running shoes. They were developed to provide a protective layer, attenuate the shock caused by the collision of the foot with the ground, and reduce local plantar pressure peaks [26]. The cushioning characteristics are modified in the midsole through material and geometry changes.

    Midsole compression stiffness and hardness

    Midsole compression stiffness, also known as hardness, is a fundamental material property that measures the deformation caused by an area load. In the past, midsoles were constructed with uniformly distributed compression stiffness. However, they can now be tailored to individually cushioned midsoles with varying properties at different locations due to the viscoelastic properties of the material [27].

    Twelve of thirty-five articles identified through our literature search considered covariates when analysing the response to differently cushioned midsoles (Fig. 4, Supplementary Table 1). Malisoux et al. considered the runner’s body mass as a covariate [28]. Athletes reported fewer injuries when running in softer midsoles, and lighter runners in hard shoes showed a greater risk of developing an RRI than heavier runners. Three articles investigated the biomechanical response of midsoles with varying hardness during different running speeds. Nigg et al. found that the vertical GRF loading rate increases with speed independent of the cushioning variations, while another study showed unchanged GRF loading rates with footwear of varying cushioning at different speeds, and yet another study showed lower GRF loading rates in harder midsoles with no dependence on running speed [29,30,31]. Running distance or running duration has been considered by five studies [32,33,34,35,36]. None of the studies found significant footwear-by-time/distance interaction effects on vertical GRF loading rates, ground contact times, peak rearfoot eversion angles, and knee flexion angle at initial contact. One article considered the runner’s foot strike pattern as a covariate [37]. Rearfoot strikers reduced the vertical GRF loading rate in a neutrally cushioned shoe, and mid- and forefoot strikers reduced the vertical GRF loading rate in a minimal shoe [37]. We identified one study considering the stiffness of the running surface as a covariate [38]. However, no main and interaction effects were observed in ground contact time and knee flexion angle at touchdown. Another study analysed the effect of surface inclination and midsole cushioning [39]. The authors showed that vertical GRF loading rates are equal when running on different surfaces with either a neutral or a cushioned running shoe. Although studies have examined a variety of covariates, there is much conjecture in the literature regarding their influence on biomechanical measures related to RRI, and no conclusive evidence to suggest that any one covariate is more important than another.

    When considering the effects of midsole hardness on BRFs without considering covariates, five studies found reduced peak rearfoot eversion in harder midsoles than in softer midsoles [40,41,42,43,44]. However, four studies found unchanged peak rearfoot eversion angles when running in soft and hard midsoles [34, 45,46,47]. Four studies reported that different midsole hardness could not systematically affect the rearfoot eversion range of motion [40, 44, 45, 48]. In contrast, one study found a reduction in the rearfoot eversion range of motion in hard midsoles [47], and another study found that the range of motion of the rearfoot was lower when runners were running in softer midsoles [49]. Conflicting findings were also observed for the rearfoot inversion angle at initial ground contact. One study found a reduction in rearfoot inversion when running in soft midsoles [40], and others found reduced inversion angles when running in hard midsoles [40, 48]. Conflicting findings have also been reported for the vertical GRF loading rate. Some studies found an increased vertical GRF loading rate in more cushioned than less cushioned shoes [29, 34]. Other studies found no effects of cushioning [46, 50,51,52], while others found decreased vertical GRF loading rate in cushioned shoes [41]. Only a few studies were identified addressing the effects of different cushioning characteristics on BRFs at more proximal joints. One article’s qualitative data showed that the knee abduction angle during the stance phase was reduced when running in softer than harder midsoles [53]. In contrast, another study found lower peak knee abduction angles when the midsole was manufactured with harder material [47]. A study by Malisoux and colleagues found that both soft and hard midsoles did not change peak hip abduction angles and moments and peak hip internal rotation angles [45]. When considering ground contact time as BRF for PFPS, most studies found no effect of midsole cushioning [29, 36, 38, 45, 49, 51, 54,55,56]. Overall, studies analyzing BRFs without considering covariates, resulted in inconsistent and conflicting findings. Interestingly, the footwear comfort perception reported by participants tends to be higher in regions where softer material is allocated than in those with harder materials [42, 49, 57, 58].

    In summary, the current literature suggests that the midsole hardness can potentially reduce the overall injury risk when adjusted to the runner’s body mass. Reduction in vertical GRF loading rates and subsequent minimizing PF injury risk could be achieved by individualising midsole cushioning to the runner’s foot strike pattern. Specifically, rearfoot strikers might benefit from cushioned shoes, while fore- and midfoot strikers could find minimal shoes advantageous. The lower vertical GRF loading rates observed in neutral shoes compared to cushioned shoes when running downhill suggest that customised midsole cushioning tailored to a runner’s training terrain could benefit runners with a PF history. Based on the limited literature, surface stiffness, running distance, and fatigue might be less important when individualising midsole hardness. Harder midsoles can reduce BRFs associated with MTSS, TSF, AT (rearfoot eversion movement), and ITBS (ground contact times). Indications that different shoe cushioning may alter vertical GRF loading rates are contradictory, and BRFs at more proximal joints have not been well studied.

    Midsole geometry

    Running footwear is often designed with a height gradient from the heel to the forefoot. Running shoes are defined by their heel and forefoot heights, with the difference between the two known as the heel-toe drop. Unlike neutral or motion-control shoes, minimal footwear is typically designed with a lower heel-toe drop. An increase in footwear minimalism generally shifts the foot strike pattern of rearfoot strikers towards a mid- or forefoot strike pattern, and it is further assumed to reduce impact loading parameters [59, 60].

    We identified eighteen articles investigating the effects of geometrical midsole modifications matching our inclusion criteria (Fig. 4, Supplementary Table 2). Out of the eighteen articles, nine accounted for a covariate. The runner’s experience was considered in one article [61]. During a six-month follow-up, it was shown that occasional runners (< 6 months running experience) had reduced injury rates, and recreational runners (≥ 6 months running experience) had increased injury rates when running in footwear with lower heel-toe drop. A subset of this data demonstrated that midsoles with different heel-toe drops were not able to reduce peak rearfoot eversion angle and ground contact time [62]. However, runners who trained for six months in footwear with higher heel-toe drops increased the peak knee abduction angle. On the contrary, runners who trained for six months in footwear with lower heel-toe drops reduced the peak knee abduction angle. Running surface as a covariate was considered by one study [63]. The researchers found smaller knee flexion angles for larger heel-toe drops when running on a treadmill. However, when running overground, the knee flexion angle was not changed when running in shoes with different heel-toe drops. The authors found that increasing the heel-toe drop led to lower vertical GRF loading rates overground, but decreasing the heel-toe drop reduced vertical GRF loading rates during treadmill running. Different running speeds as a covariate were considered by four articles [64,65,66,67]. One study found no changes in the knee flexion angle at initial contact when running at different speeds in midsoles with different heel-toe drop designs [64]. Another study showed that while ground contact time decreased with increasing speed, increasing the heel-toe drop resulted in increased contact time [65]. Other researchers also showed similar results when systematically altering running speed and heel-toe drop [66]. Running speed did not influence the effects of heel-toe drop modifications on vertical GRF loading rates or time spent in rearfoot eversion [67]. The interaction effects of running time and geometrical midsole modifications were investigated in two studies using the same data set [68, 69]. However, neither of the studies reported interaction effects on included BRFs (rearfoot movement, contact time, and knee flexion angle at initial ground contact). Nevertheless, both studies reported longer ground contact times, lower rearfoot eversion range of motion, and greater knee flexion angles at initial contact in thicker than thinner midsoles.

    Concerning the general effects of midsole geometries on BRFs without considering covariates, most of the included studies have addressed the effect of midsole geometry on GRF parameters. An increase in heel-toe drop has been reported to reduce vertical GRF loading rates [70,71,72,73]. Diverse results have been reported for midsole thickness, for which one study found lower vertical GRF loading rates in thicker than thinner midsoles [74], whereas another study could not identify any differences [75]. Three studies showed that geometrical changes at the midsole do not affect rearfoot inversion at touchdown [68,69,70]. Three articles showed that the knee flexion angle at touchdown remains unchanged independent of geometrical midsole configurations [72, 75, 76]. Only one study collected comfort perception data from fifteen male runners [77]. However, no difference in comfort was observed when the heel-toe drop was systematically altered.

    Summarising the results, individualisation of heel-toe drop based on runner experience may reduce the risk of RRI. Although the underlying biomechanical mechanism remains unknown, a gradual transition from shoes with different heel-to-toe drops may allow adequate adaptation of the biological tissues. Running surfaces can affect the response to heel-toe drop alterations by influencing vertical GRF loading rates and knee flexion angles. Runners with a history of PF training on treadmills may benefit from shoes with a lower heel-toe drop, while those with a history of ITBS may benefit from a higher drop. During fatigue, geometric midsole modifications may not affect rearfoot eversion movement or ground contact times. Thinner midsoles with a lower heel-toe drop may reduce ground contact times, peak rearfoot eversion angle and rearfoot eversion duration. Hence, these modifications might be recommended for runners with a risk or a history of PFPS, TSF, or MTSS. Moreover, thicker midsoles with a higher heel-toe drop might shift BRFs related to AT and PF (rearfoot eversion range of motion and vertical GRF loading rate) to potentially less critical BRF magnitudes.

    Motion control features

    Motion control, also called stability, in footwear refers to how the shoe limits pronation (calcaneal eversion) or supination (calcaneal inversion) during the support phase. Much research has been devoted to FDF that purports to control pronation or eversion motion, motivated by the retrospective observations that increased pronation angle is associated with RRI [10, 78,79,80]. Over the initial period of footwear research, various midsole technologies were designed to increase rearfoot stability, including altering the midsole hardness, location of material inserts, flares, arch support systems, and postings. One of the few identified studies utilized a randomized controlled trial with a six-month follow-up. The findings revealed that recreational runners with a motion control shoe developed fewer RRI than runners receiving a standard running shoe [15]. Interestingly, motion-control shoes’ effectiveness in reducing RRI development was more pronounced for runners with pronated feet, indicating some potential for footwear individualisation.

    Postings

    Postings in athletic footwear incorporate elements with higher material densities in the medial rearfoot region and have been reported to limit rearfoot eversion [81]. Unlike wedges, postings are designed without gradual height differences [82].

    Three of seven articles identified through our literature search considered covariates in their analysis (Fig. 4, Supplementary Table 3). The runner’s age was considered by one article [83]. Medial posts effectively reduced the amount of rearfoot eversion in older compared to younger female runners, while vertical GRF loading rates, peak knee abduction moments, and peak knee internal rotation angles remained unchanged. When considering the runners’ fatigue as a covariate, two articles found that rearfoot eversion movement (peak and range of motion) was lower when running in a medially posted than in a neutral running shoe when the runner’s fatigue increased [84, 85].

    When not considering covariates or subgroups of runners, medial postings can reduce peak rearfoot eversion angles and eversion range of motion [86, 87]. Peak knee internal rotation angles are reported to be reduced when running in footwear with medial postings [83, 88]. However, footwear with postings might increase peak hip abduction moments [89]. Diverse results were found for vertical GRF loading rates. One study found lower vertical GRF loading rates in midsoles without medial posts [87], and another found unchanged vertical GRF loading rates in shoes with and without postings [83]. Some runners have perceived the harder posting material without transitions as uncomfortable, potentially resulting in unwanted changes in their biomechanics [88].

    In summary, older female runners with a history of TSF and MTSS might reduce rearfoot eversion in shoes with postings. However, medial posts do not seem to affect the risk of developing PF independent of the runners’ age since changes in vertical GRF loading rates were not observable. Based on the limited literature, posted midsoles may help minimise BRFs (rearfoot eversion movement) associated with AT, MTSS, or TSF as the runners’ fatigue state increases. The limited literature suggests that individualised postings can help runners with a history of AT, MTSS, TSF, or ITBS to reduce biomechanical risk factors. Since postings might increase vertical GRF loading rates, caution needs to be taken by runners with a history of PF.

    Wedges

    Wedges are sloped orthotic inserts, typically with mediolateral elevation, designed to increase foot stability. Mediolateral elevation under different loading conditions can be achieved by incorporating materials with different mechanical properties at distinguished locations of the wedge [90].

    Three out of the ten articles identified in the literature search included a covariate in their analysis (Fig. 4, Supplementary Table 4). One study considered running duration (0–30 min) as a covariate [91]. Independent of the running duration, medially wedged insoles produced lower knee abduction angular impulses than laterally wedged insoles. Another study considered different standing calcaneal angles and injury history as covariates [92]. However, wearing differently wedged insoles showed no effect on female runners’ 3D knee and hip kinematics. Anterior knee pain as a covariate and the response to differently wedged insoles were considered by one article [93]. Independent of knee pain, running in medially wedged insoles reduced maximal rearfoot eversion and range of motion compared to running in footwear without wedges. None of the studies personalised the wedges to the runner’s individual foot anatomy; instead, they used pre-fabricated wedges, which may have confounded these results.

    Seven articles were identified investigating the effect of wedged insoles on BRFs without considering covariates. In a study in which the wedges were customised to individual dynamic barefoot plantar pressure data, all but two subjects reduced peak rearfoot eversion angles compared to footwear without wedges [94]. This finding suggests that wedges bear high potential when individualised to foot pressure mapping. Pre-fabricated medial wedges have proven effective in decreasing maximal rearfoot eversion angles and eversion range of motion [94,95,96,97]. When comparing footwear with and without wedges, non-systematic changes in vertical GRF loading rates and knee abduction angular impulse have been reported [95, 96, 98, 94, 99, 100]. When the mediolateral elevation was systematically altered, no perceived comfort and stability changes were reported [95]. Moreover, neither medially nor laterally wedged insoles were able to relieve runners of patellofemoral pain [99]. One study introduced forefoot wedges with systematic changes in elevation; however, no changes in ground contact times were reported [101].

    In summary, the response to medially wedged insoles is independent for shorter running durations (< 30 min) but may help runners with a history of PFPS to minimise knee abduction angular impulses; however, the effect for longer running durations (> 30 min) remains unknown. The limited literature shows that joint alignments, injury history, and knee pain are less relevant covariates when individualising wedged insoles. Medially wedged insoles might sufficiently limit rearfoot eversion movement and support runners with a history of AT, TSF, and MTSS to reduce reinjury. To attenuate vertical GRF loading rates, runners with a history of PF might refer to other FDF modifications to reduce the overuse injury risk.

    Arch support systems

    Arch support systems help the foot by storing and releasing elastic energy and preventing arch collapse during high loading [102]. Foot arches can be classified as flat/low, normal, or high [103]. Within the three groups, low-arched runners may exhibit greater eversion movement and velocity than high-arched runners [104]. Arch support systems can be integrated into the midsole or achieved through custom-made insoles shaped into the foot arch [105].

    Our review found seven articles, four of which examined the effect of arch support systems on running biomechanics with a covariate (Fig. 4, Supplementary Table 5). Two studies used foot arch height as the covariate, and they found that high-arched runners reduced vertical GRF loading rates in a shoe without arch support, while low-arched runners reduced loading rates in a shoe with arch support. However, both foot arch types experienced reduced rearfoot eversion in a motion control shoe [106]. With a subset of this data, no changes in rearfoot eversion movements for runners with different foot arch types were observed when running in shoes with and without arch support systems during a prolonged run [107]. One article accounted for the runner’s foot strike pattern and found that rearfoot strikers decreased ground contact time in footwear without arch support [108]. In contrast, forefoot strikers reduced contact time in a shoe with arch support [108]. The same study found that forefoot strikers in minimal footwear reduced vertical GRF loading rates, but rearfoot strikers did not. Furthermore, training for three months in footwear with a custom-made arch support system reduced rearfoot eversion [105].

    We identified three articles investigating the effect of arch support systems on BRFs without considering covariates. A study involving female runners found no effect of arch support on vertical GRF loading rates, peak rearfoot eversion angles, and peak femur rotation angles [46]. Another study also found unchanged rearfoot eversion movements (peak eversion angle and rearfoot inversion at initial ground contact) and knee abduction angles when runners with AT symptoms ran in footwear with and without arch support [109]. Although BRFs were unchanged, a 92% relief of AT symptoms was reported when wearing an insole with custom-made arch support. Finally, one study found unchanged ground contact times when running in midsoles with 20 mm and 24 mm high arch support elevations [101].

    The limited literature suggests that arch support systems can potentially reduce BRFs for runners with different arch heights and a history of PF. Runner’s foot strike pattern might be considered when individualising arch support systems. When individualising arch support systems to minimise BRFs associated with PFPS (ground contact time) and PF (vertical GRF loading rate), forefoot strikers might benefit from less arch support than rearfoot strikers. Moreover, customised arch support systems enhance comfort perception without changes in peak knee abduction angles and vertical GRF loading rates. Arch support might reduce rearfoot eversion movements and thus have the potential for individualisation for runners with a history of AT, TSF, and MTSS. BRFs related to ITBS (peak femur rotation angle and peak knee abduction angles) seem to change marginally and unsystematically with arch support.

    Heel flares

    Flares can be described as a projection of the midsole and outsole extending beyond the upper [25]. Flares can be placed medially or laterally along the outline of the midsole and were introduced to alter the rearfoot eversion angle, thus increasing foot stability by changing the ankle joint moment arm [110,111,112].

    After examining all articles, we identified five matching our inclusion criteria (Fig. 4, Supplementary Table 6). None of these articles investigated the effect of a covariate.

    Concerning BRFs, one study altered the medial heel flare from 0° to 15°, and 30°. The 2D video-based analysis indicated higher rearfoot eversion movement in footwear without heel flares [81]. In the same study, runners running in shoes with the most extreme medial heel flare modification had, on average, lower rearfoot eversion range of motion than in shoes with less or without heel flares. These findings were supported by other research showing that footwear with heel flares can reduce the magnitude of rearfoot eversion across the entire stance phase but does not seem to reduce vertical GRF loading rates [110, 112, 113]. On the contrary, one study with only five runners did not show that rearfoot eversion movement (at initial ground contact, peak, and range of motion) changes when running in footwear with different heel flares [111]. From a perception perspective, heel flares can improve perceived foot stability [112].

    None of the articles considered covariates (e.g., foot strike pattern), highlighting future research potential. Although we found diverse results regarding rearfoot eversion movement, midsoles with heel flares might reduce BRFs linked to AT, TSF, or MTSS. Based on the very limited body of literature, midsoles with heel flares are insufficient for reducing vertical GRF loading rates, and individualised heel flares may not target runners with a history of PF.

    Crash pads

    Crash pads are elements incorporated into the posterior-lateral midsole using softer foams, segmented geometries, air pockets, or gel-filled patches. Crash pads in the rearfoot area aim to attenuate the GRF and reduce the GRF’s lever arm to the ankle joint [114].

    After assessing articles for their eligibility, we identified three articles matching our inclusion criteria (Fig. 4, Supplementary Table 7). Out of the three articles, one study considered the fatigue status of female runners as a covariate. As the runners’ fatigue increased, wearing footwear without crash pads increased vertical GRF loading rates compared to the non-fatigue state. However, running in footwear with crash pads maintained consistent vertical GRF loading rates, even as the runners’ fatigue increased. [115]. The same study found no effect of fatigue on the peak free moment amplitude.

    When not considering covariates, two studies found reduced rearfoot inversion angles at touchdown in footwear with smaller compared to larger crash pad dimensions. However, there were no differences in peak rearfoot eversion angles during the stance phase of running and unsystematic changes in vertical GRF loading rates [114, 116]. Crash pad modifications did not affect the peak free moment amplitude, ground contact time, and rearfoot eversion range of motion [114,115,116]. Changes in crash pad dimensions do not seem to influence the runner’s comfort perception [114]. However, they may provide an essential tool for individualisation to tune midsole cushioning properties without increasing stack height which has been shown to increase rearfoot eversion [81].

    Fatigue seems to be a relevant covariate when individualising crash pads to minimise vertical GRF loading rates, thus, might lower the risk of developing PF. However, runners with a history of TSF might need other individualised FDF to lower peak free moment amplitudes. Increasing crash pad height might help runners with plantar fascia complaints by lowering the vertical GRF loading rates. Runners with a history of AT, TSF, or MTSS might benefit from crash pads by reducing rearfoot eversion movement. Surprisingly, although the FDF aimed at attenuating the peak impulse, we have identified only two studies that have analysed vertical GRF loading rate as BRF.

    Other footwear design features

    Rocker

    Rockers in running shoes aim to reduce the strain on the toes, foot, and ankle by altering the midsole’s curvature in the anterior–posterior direction, positioning the apex near the metatarsal heads, and enhancing the midstance-to-push-off transition for a smoother heel-to-toe rolling motion [117].

    Each of the three identified articles considered a covariate in their analysis (Fig. 4, Supplementary Table 8). One study considered running speeds as a covariate. Although running at higher speeds increases the vertical GRF loading rate, no changes in GRF loading rates were observed between shoes with and without rocker [118]. Two studies considered the foot strike pattern and found that a toe spring starting closer to the midfoot reduced pressure in the forefoot compared to a standard rocker placed at 65% of the shoe length [119]. However, runners perceived the traditional rocker as more comfortable. When compared to shoes without rockers, one study found that a rocker shoe reduced ground contact time but did not affect knee flexion angles at initial ground contact [120].

    The number of studies addressing injury-specific BRFs and the effects of rocker designs is limited. Rockers involve different levels of FDF (stack height, cushioning), and therefore it is difficult to assign a specific feature to a specific BRF. More research is needed to understand if certain covariates can cause a specific change in BRFs and how different FDFs that combine a rocker design need to be tuned for individualisation.

    Outsole profile

    A shoe’s outsole interacts with the running surface and requires attributes like traction, waterproofness, durability, and puncture resistance [121]. Material robustness might be related to running shoe comfort, and high traction might increase free moment amplitudes associated with TSF [122].

    After assessing all articles for eligibility, we could not identify any articles matching our predefined inclusion criteria (Fig. 4). Future studies might use wearable sensors or markerless tracking systems to analyse runners wearing shoes with different outsole profiles on natural surfaces.

    Flex grooves

    Flex grooves and zones are included in outsoles and midsoles to enhance flexibility, facilitating metatarsophalangeal joint movement and shock absorption. Their placement is essential for the joint’s variable axis and should be individualised based on foot measurements. Recent 3D measurements indicate significant variation, underscoring the need for personalized flexible zones [123].

    Our literature search identified one article matching our predefined inclusion criteria (Fig. 4, Supplementary Table 9). This article considered running speed as a covariate. In this study, the midsole flexibility was altered by cuts with different orientations at the heel region. Although interaction effects were only marginal when jogging or running in footwear with different groove designs, a 10% lower vertical GRF loading rate was observed in the midsole with grooves compared to the midsoles without grooves at the rearfoot [124]. Interestingly, footwear with greater flexibility is perceived as more comfortable than midsoles with less flexibility [125, 126].

    While there is limited research on the impact of flex grooves on relevant BRFs for common RRI, one identified article found that they can reduce vertical GRF loading rates, suggesting that flex grooves may be customised for runners with PF.

    Longitudinal bending stiffness

    The longitudinal bending stiffness can impact the running economy by optimising energy return and kinematics of the metatarsal joint and force application [127,128,129,130,131]. The bending stiffness can be modified by adding reinforcement materials or changing the geometry of stiff midsole compounds. The optimal bending stiffness depends on factors such as running speed and body weight [128, 132].

    Our literature search identified eleven articles, of which four accounted for a covariate (Fig. 4, Supplementary Table 10). All four articles considered running speed as a covariate. None of these articles found a significant interaction effect on BRFs when running in footwear with different longitudinal bending stiffness at different running speeds [133,134,135,136]. Independent of running speed, studies reported reduced ground contact times when running in shoes with lower bending stiffness, while one article found unchanged ground contact times [136].

    When not considering covariates, three studies found no changes in the GRF braking impulse when running in shoes with different bending stiffness [135, 137, 138]. On the contrary, a reduction in GRF braking impulse in footwear with higher bending stiffness was found in one study [134]. Eight articles found a reduction in the ground contact time [130, 133,134,135, 137,138,139], and two found unchanged ground contact times [134, 140] when running in midsoles with lower bending stiffness. Although studies found lower vertical GRF loading rates [140] and increased comfort perception [135] when athletes ran in more flexible than stiffer midsoles, the relationship between BRFs and injury development when altering the longitudinal bending stiffness has not been sufficiently studied yet, but first studies have evolved showing that bones stress injuries might increase when switching to footwear with carbon fibre plates [18].

    The limited body of literature suggests that fitting longitudinal bending stiffness to the runner’s needs may help with treating PFPS. While reduced bending stiffness can reduce ground contact time, higher stiffness can reduce ground reaction force braking impulse. However, injury prevention and reinjury risk minimisation under the light of different longitudinal bending stiffness has been insufficiently investigated. Furthermore, flexible midsoles with lower longitudinal bending stiffness might reduce vertical GRF loading rates and potentially help runners with a history of PF.

    The upper

    The running shoe upper is comprised of a textile fabric and lacing system that couple the foot and shoe, with reinforcement materials used for stability and breathability. An optimal fit depends on individual foot morphology, while insufficient coupling can negate benefits from other design features. Moreover, excessive pressure can affect comfort by restricting blood supply, making individualisation important [141]. Since foot dimensions differ across sexes, ages, and ethnic origins, individualised upper bears great potential for individualisation [142].

    Upper fabric

    Our systematic literature search identified two articles investigating the effect of different upper modifications (Fig. 4, Supplementary Table 11). None of the articles considered covariates [53, 143].

    The data indicates that a soft-sewed structured fabric reduces knee abduction angles and vertical GRF loading rates compared to a minimalist heat fusion fabric. Furthermore, the ground contact time was reduced when running in minimalist heat fusion fabric.

    The current body of literature is insufficient to give recommendations for upper individualisation concerning the reduction of BRFs. Based on the limited results, upper materials might be individualised to the runner’s preference.

    Lacing

    Five articles have investigated the effect of lacing on the lower extremity joint biomechanics or subjective comfort perception (Fig. 4, Supplementary Table 12).

    One of five studies considered the runner’s experience as a covariate. The researchers found that low-level runners perceived an irregularly (skipping eyelets) laced running shoe as more stable and comfortable than high-level runners who preferred a regular high and tight lacing pattern [144].

    We identified four studies analysing BRFs without accounting for covariates. According to a study, running shoes with traditional lacing and elastic upper material were perceived as more comfortable than footwear without lacing [145]. When running in shoes with various lacings, two studies found no significant difference in the rearfoot eversion angle at initial contact [145, 146]. The same studies found a reduction in the peak rearfoot eversion angle when running in traditionally laced shoes compared to those without traditional lacing. However, another study systematically changed lacing patterns and could not find any differences in the peak rearfoot eversion angle [147]. Different types of lacing patterns, particularly high- and tightly-laced shoes, have been shown to reduce vertical GRF loading rate at the cost of comfort [144, 148].

    Studies analysing BRFs and considering relevant covariates, e.g., foot shape, are required in the future. Notably, no studies have measured the foot-shoe coupling or the relative movement of the foot within the shoe, highlighting the potential for future research to determine individualised fits and their interactions with other FDF. Since peak rearfoot eversion angles and vertical GRF loading rates are reported to be lower when running in tightly and high-laced shoes, runners with a history of MTSS and TSF might target individualised lacing systems.

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  • Osteoarthritis: Causes, Symptoms, and Treatment

    Osteoarthritis: Causes, Symptoms, and Treatment

    As we age, our bodies go through various changes, and one of the most common conditions that develop is osteoarthritis. Osteoarthritis is a type of arthritis that affects millions of people worldwide, and it occurs when the protective cartilage that cushions the ends of our bones wears down over time. Although it can damage any joint, the disorder most commonly affects joints in our hands, knees, hips, and spine.

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    Understanding Osteoarthritis is crucial for anyone who may be experiencing joint pain or stiffness. This condition is often referred to as “wear and tear” arthritis, and it occurs when the cartilage within a joint begins to break down, causing the underlying bone to change. These changes usually develop slowly and get worse over time, leading to pain, stiffness, and difficulty moving the joint.

    Key Takeaways

    • Osteoarthritis is a type of arthritis that affects millions of people worldwide, and it occurs when the protective cartilage that cushions the ends of our bones wears down over time.
    • This condition is often referred to as “wear and tear” arthritis, and it occurs when the cartilage within a joint begins to break down, causing the underlying bone to change.
    • Symptoms of osteoarthritis include joint pain, stiffness, and difficulty moving the joint.

    Understanding Osteoarthritis

    Osteoarthritis is a degenerative joint disease that affects millions of people worldwide. It is the most common form of arthritis, and it occurs when the protective cartilage that cushions the ends of the bones wears down over time. This can cause discomfort when moving the joint, and it can lead to stiffness and pain.

    Osteoarthritis is also known as “wear and tear” arthritis or degenerative joint disease. It can damage any joint in the body, but it most commonly affects joints in the hands, knees, hips, and spine. In some cases, osteoarthritis can also affect the neck, shoulders, and ankles.

    The main cause of osteoarthritis is the breakdown of joint cartilage, which can be caused by a combination of factors such as heredity, obesity, injury, and overuse. Cartilage is a tough, flexible tissue that covers the ends of bones where they meet to form a joint. It acts as a cushion and helps to absorb shock when the joint is used.

    When cartilage breaks down, the underlying bone can also change, leading to the development of osteoarthritis. The changes usually develop slowly and get worse over time. As the condition progresses, the joint may become painful and stiff, making it difficult to move.

    There is no cure for osteoarthritis, but there are several treatments available to help manage the symptoms. These include medications, physical therapy, and surgery. In some cases, lifestyle changes such as losing weight or exercising regularly can also help to reduce the symptoms of osteoarthritis.

    In conclusion, osteoarthritis is a common joint disease that affects millions of people worldwide. It is caused by the breakdown of joint cartilage, and it can lead to pain and stiffness in the affected joints. While there is no cure for osteoarthritis, there are several treatments available to help manage the symptoms and improve quality of life.

    Symptoms of Osteoarthritis

    Osteoarthritis is a type of arthritis that affects the joints. It is a degenerative disease that causes the cartilage in the joints to break down, leading to pain, stiffness, and other symptoms. In this section, we will discuss the most common symptoms of osteoarthritis.

    Pain and Stiffness

    The most common symptoms of osteoarthritis are pain and stiffness in the affected joints. The pain may be mild or severe and can be felt during or after movement. Joint stiffness is most noticeable in the morning or after being inactive for a period of time. The affected joint may also feel tender when light pressure is applied to it.

    Decreased Range of Motion

    Osteoarthritis can also cause a decreased range of motion in the affected joint. This means that you may not be able to move the joint as freely as you used to. This can make it difficult to perform daily tasks, such as getting dressed or reaching for objects.

    Swelling and Tenderness

    Swelling and tenderness are also common symptoms of osteoarthritis. The affected joint may become swollen and tender to the touch. This can make it difficult to move the joint and can cause discomfort.

    Bone Spurs

    Osteoarthritis can also cause the growth of bone spurs around the affected joint. These bone spurs can cause additional pain and can make it difficult to move the joint.

    Complications

    Osteoarthritis can lead to complications, such as disability and falls. In some cases, the pain and stiffness caused by osteoarthritis can make it difficult to perform daily tasks, such as walking or climbing stairs. This can lead to disability and a decreased quality of life. Falls are also a common complication of osteoarthritis, as the pain and stiffness can cause a loss of balance.

    Joint Damage

    Osteoarthritis can also cause damage to the joint over time. The cartilage in the affected joint can wear down, leading to bone-on-bone contact. This can cause further pain and damage to the joint.

    Other Symptoms

    Other symptoms of osteoarthritis may include joint inflammation, a cracking or popping sound in the joint, and the formation of cysts around the joint.

    Risk Factors

    There are several risk factors that can increase your likelihood of developing osteoarthritis. These include age, obesity, joint injuries, and genetics.

    In summary, osteoarthritis is a degenerative disease that affects the joints. The most common symptoms of osteoarthritis include pain, stiffness, decreased range of motion, swelling, tenderness, bone spurs, complications, joint damage, and other symptoms. If you are experiencing any of these symptoms, it is important to seek medical attention to receive an accurate diagnosis and appropriate treatment.

    Frequently Asked Questions

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    What are the risk factors for developing osteoarthritis?

    We can develop osteoarthritis due to various factors such as age, obesity, previous injuries, and genetics. Women are also more likely to develop osteoarthritis than men.

    What are the different types of osteoarthritis?

    There are different types of osteoarthritis that can affect different parts of the body. Some of the common types include knee osteoarthritis, hip osteoarthritis, and hand osteoarthritis.

    What are some common medications used to treat osteoarthritis?

    There are various medications that can help manage osteoarthritis symptoms such as pain and inflammation. Some common medications include acetaminophen, nonsteroidal anti-inflammatory drugs (NSAIDs), and corticosteroids.

    What are some ways to prevent osteoarthritis?

    While we cannot prevent osteoarthritis entirely, we can take steps to reduce our risk of developing it. Maintaining a healthy weight, staying active, and avoiding injuries can help prevent osteoarthritis.

    How does osteoarthritis affect the body?

    Osteoarthritis can cause pain, stiffness, and decreased range of motion in the affected joints. It can also lead to the breakdown of joint cartilage and the development of bone spurs.

    What are some strategies to manage osteoarthritis pain?

    There are various strategies that can help manage osteoarthritis pain such as exercise, physical therapy, and hot/cold therapy. We can also use assistive devices like braces or canes to help reduce joint stress.

    Add Tables

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    We can use tables to organize and present information about osteoarthritis in a clear and concise manner. Here are some examples of tables that can be useful:

    Table 1: Common Symptoms of Osteoarthritis

    SymptomDescription
    PainPain in the affected joint, especially during or after movement.
    StiffnessStiffness in the affected joint, especially after periods of inactivity.
    SwellingSwelling and tenderness in the affected joint.
    Cracking or popping soundsCracking or popping sounds when moving the affected joint.
    Limited range of motionDifficulty moving the affected joint through its full range of motion.

    Table 2: Risk Factors for Osteoarthritis

    Risk FactorDescription
    AgeThe risk of developing osteoarthritis increases with age.
    GenderWomen are more likely to develop osteoarthritis than men.
    ObesityExcess weight puts extra stress on the joints, increasing the risk of osteoarthritis.
    Joint injuriesPrevious joint injuries or surgeries can increase the risk of osteoarthritis.
    GeneticsOsteoarthritis may run in families.

    Table 3: Treatment Options for Osteoarthritis

    TreatmentDescription
    MedicationsPain relievers, nonsteroidal anti-inflammatory drugs (NSAIDs), and corticosteroids can help manage pain and inflammation.
    Physical therapyExercises and stretches can help improve joint flexibility and strength.
    Assistive devicesBraces, canes, and other devices can help take pressure off the affected joint.
    SurgeryJoint replacement surgery may be necessary in severe cases.

    By using tables, we can easily compare and contrast different symptoms, risk factors, and treatment options for osteoarthritis. This can help us make informed decisions about managing this common joint condition.

  • Knee Anatomy and Functions And the Key Components of Your Knee

    Knee Anatomy and Functions And the Key Components of Your Knee

    As a physical therapist, I have seen many patients with knee injuries and conditions. Understanding the anatomy and function of the knee joint is essential to prevent injuries, manage pain, and recover from surgery. In this article, I will explain the basic structure of the knee, the role of ligaments and tendons, and the muscles responsible for movement.

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    The knee joint is the largest joint in the body and connects the thigh bone (femur) to the shin bone (tibia). The kneecap (patella) is a small bone that sits in front of the knee joint and protects the joint. The knee joint is a hinge joint that allows for flexion and extension of the leg. It also has some rotational movement, which is important for activities such as walking and running.

    The knee joint is supported by several ligaments and tendons. Ligaments are tough bands of tissue that connect bones to bones, while tendons connect muscles to bones. The ligaments and tendons around the knee joint work together to provide stability and support to the joint. In the next section, I will discuss the role of these structures in more detail.

    Key Takeaways

    • The knee joint is the largest joint in the body and allows for flexion, extension, and some rotational movement.
    • The knee joint is supported by ligaments and tendons that provide stability and support to the joint.
    • Understanding the basic structure and function of the knee joint is essential for preventing injuries, managing pain, and recovering from surgery.

    Basic Structure of the Knee

    As the largest joint in the body, the knee is a complex structure that allows us to walk, run, jump, and perform other physical activities. It is a synovial joint, meaning it contains a fluid-filled capsule that lubricates the joint and reduces friction during movement.

    Bones and Joints

    The knee joint is formed by the articulation of three bones: the femur, tibia, and patella. The femur, or thigh bone, is the longest bone in the body and forms the upper part of the knee joint. The tibia, or shin bone, is the larger of the two bones in the lower leg and forms the lower part of the knee joint. The fibula is the smaller bone in the lower leg and is not directly involved in the knee joint.

    The knee joint is actually two joints in one: the tibiofemoral joint and the patellofemoral joint. The tibiofemoral joint is the main joint between the femur and tibia, while the patellofemoral joint is the joint between the patella and the femur.

    Patella

    The patella, or kneecap, is a sesamoid bone that sits in front of the knee joint and helps to protect the knee and improve the leverage of the quadriceps muscle. The patella is unique in that it is not directly attached to any other bone in the body. Instead, it is connected to the quadriceps tendon and the patellar ligament.

    In summary, the knee joint is a complex structure that is formed by the articulation of three bones: the femur, tibia, and patella. The knee joint is actually two joints in one: the tibiofemoral joint and the patellofemoral joint. The patella, or kneecap, is a sesamoid bone that sits in front of the knee joint and helps to protect the knee and improve the leverage of the quadriceps muscle.

    Knee Ligaments and Tendons

    The knee joint is stabilized and supported by a network of ligaments and tendons. These structures work together to provide strength and stability to the knee joint, allowing us to perform various activities such as walking, running, and jumping.

    Collateral Ligaments

    The collateral ligaments are located on the sides of the knee joint. The medial collateral ligament (MCL) is located on the inner side of the knee, while the lateral collateral ligament (LCL) is found on the outer side. These ligaments help to prevent excessive side-to-side movement of the knee joint.

    Cruciate Ligaments

    The cruciate ligaments are located inside the knee joint and cross each other to form an “X” shape. The anterior cruciate ligament (ACL) is located in the front of the knee, while the posterior cruciate ligament (PCL) is located at the back. These ligaments help to prevent excessive forward and backward movement of the knee joint.

    Tendons

    The patellar tendon and quadriceps tendon are two important tendons that are located in the knee joint. The patellar tendon connects the patella (kneecap) to the tibia (shinbone), while the quadriceps tendon connects the quadriceps muscle to the patella. These tendons help to provide stability to the knee joint and allow us to perform various movements such as jumping and climbing stairs.

    In summary, the knee joint is stabilized and supported by a network of ligaments and tendons. The collateral ligaments help to prevent excessive side-to-side movement of the knee joint, while the cruciate ligaments help to prevent excessive forward and backward movement. The patellar and quadriceps tendons provide stability to the knee joint and allow us to perform various movements.

    Muscles and Movement of the Knee

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    The knee joint is a hinge joint that allows for flexion and extension of the lower leg. The movement of the knee is controlled by a complex system of muscles, tendons, and ligaments that work together to stabilize and move the joint.

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    Anatomical illustration of the human knee joint, showing all the components along with their names. This includes the bones, ligaments, cartilage, and tendons, with clear labels for each part such as the femur, tibia, fibula, patella, meniscus, and various ligaments and tendons.

    Quadriceps Muscles

    The quadriceps muscles are a group of four muscles located on the front of the thigh that work together to extend the knee joint. These muscles include the rectus femoris, vastus lateralis, vastus intermedius, and vastus medialis. The rectus femoris also works to flex the hip joint.

    Hamstring Muscles

    The hamstring muscles are a group of three muscles located on the back of the thigh that work together to flex the knee joint. These muscles include the biceps femoris, semitendinosus, and semimembranosus. The gracilis muscle also works to flex the knee joint.

    Movements of the Knee

    The knee joint allows for a variety of movements, including flexion, extension, lateral rotation, and medial rotation. Flexion is the movement that brings the heel towards the buttocks, while extension is the movement that straightens the leg. Lateral rotation is the movement that turns the lower leg outward, while medial rotation is the movement that turns the lower leg inward.

    The popliteus muscle is a small muscle located at the back of the knee joint that works to unlock the knee joint during flexion. The flexors and extensors of the knee joint work together to stabilize the joint during movement.

    The tibiofemoral joint is the main joint of the knee, while the patellofemoral joint is the joint between the kneecap and the femur. The articularis genus muscle is a small muscle located at the front of the knee joint that works to pull the synovial membrane of the joint upward during extension.

    The gastrocnemius and plantaris muscles are located at the back of the knee joint and work to plantarflex the ankle joint. Instability of the knee joint can lead to pain and difficulty with activities such as running and walking.

    Knee Injuries and Treatment

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    Common Knee Injuries

    The knee is a complex joint that is susceptible to a variety of injuries. Some common knee injuries include:

    • Anterior Cruciate Ligament (ACL) Tear: This is a common injury that occurs when the ACL is stretched or torn. It can happen during sports that involve sudden stops or changes in direction, such as basketball or soccer. Symptoms include pain, swelling, and instability in the knee.
    • Meniscus Tear: The meniscus is a piece of cartilage that helps cushion the knee joint. A tear can occur when the knee is twisted or bent forcefully. Symptoms include pain, swelling, and difficulty moving the knee.
    • Patellar Tendinitis: This is an injury to the tendon that connects the kneecap to the shinbone. It is often caused by overuse and can result in pain and swelling in the front of the knee.

    how to prevent knee injuries and arthritis

    SectionDescription
    1.Maintain a healthy weight to reduce stress on the knee joint.
    2.Wear appropriate shoes for the activity you are doing.
    3.Warm up before exercising to increase blood flow to the muscles.
    4.Use proper technique when exercising to avoid unnecessary stress on the knee joint.
    5.Incorporate exercises that strengthen the muscles around the knee joint.
    6.Avoid activities that put excessive stress on the knee joint, such as jumping or running on hard surfaces.
    7.Take breaks during activities to rest and stretch the knee joint.
    8.Use knee pads or braces for added support during high-impact activities.
    9.Stay hydrated to help keep the joints lubricated.
    10.Consult with a healthcare professional before starting a new exercise program.

    Treatment and Rehabilitation

    Treatment for knee injuries varies depending on the severity and type of injury. Some common treatments include:

    • Rest: Resting the knee and avoiding activities that aggravate the injury can help reduce pain and swelling.
    • Ice: Applying ice to the knee can help reduce pain and swelling. Ice should be applied for 15-20 minutes at a time, several times a day.
    • Physical therapy: Physical therapy can help strengthen the muscles around the knee joint and improve flexibility and range of motion.
    • Medication: Over-the-counter pain relievers, such as ibuprofen or acetaminophen, can help reduce pain and swelling.

    In some cases, surgery may be necessary to repair a knee injury. Rehabilitation after surgery may include physical therapy and exercises to help regain strength and range of motion.

    Overall, it is important to take steps to prevent knee injuries and to seek treatment promptly if an injury does occur. With proper care and treatment, many knee injuries can be successfully treated, allowing individuals to return to their normal activities.

    Frequently Asked Questions

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    What is the knee joint called?

    The knee joint is a synovial joint that connects three bones: the femur, tibia, and patella. It is a complex hinge joint composed of two articulations: the tibiofemoral joint and patellofemoral joint.

    Is the knee a hinge joint?

    Yes, the knee is a hinge joint. It allows for flexion and extension, as well as a small degree of medial and lateral rotation.

    What are the 3 most commonly injured knee structures?

    The three most commonly injured knee structures are the anterior cruciate ligament (ACL), medial collateral ligament (MCL), and meniscus.

    What are the major anatomical features of the knee?

    The major anatomical features of the knee include bones (femur, tibia, and patella), cartilage, ligaments, tendons, and muscles.

    What is the functional anatomy of the knee?

    The knee joint is responsible for weight-bearing and movement, allowing for flexion and extension, as well as a small degree of medial and lateral rotation. The major muscles involved in knee movement include the quadriceps, hamstrings, and calf muscles.

    What are the symptoms of a torn ligament in your knee?

    Symptoms of a torn ligament in your knee include pain, swelling, instability, and difficulty bearing weight. Depending on the severity of the tear, surgery may be necessary to repair the ligament.

  • 2024-2025 Orthopedic Value-Based Healthcare Research Fellowship

    The Fellow will collaborate with department faculty on research projects related to the design, implementation and dissemination of value-based care models, outcome measurement (including the effect of interventions on patient-reported outcomes), costs of care, impact of psychosocial aspects in conditions to the musculoskeletal system, advances in shared decision-making and patient and caregiver engagement, and the adoption of digital health solutions.

    Faculty

    The Fellow will work directly with several leaders in healthcare innovation, including:

    • Kevin Bozic, MD, MBA, professor and chairman of the Department of Surgery and Perioperative Care
    • David Ring, MD, PhD, Associate Dean of Comprehensive Care; Professor of Surgery and Psychiatry
    • Karl Koenig, MD, MS, associate professor and executive director of the Musculoskeletal Institute
    • Prakash Jayakumar, MBBS, PhD, Assistant Professor and Director of Value-Based Healthcare and Outcomes Measurement

    Key Responsibilities and Fellowship Functions

    1. Research: Core research tasks include the development of research protocols, administration of Institutional Review Board (IRB) applications, patient recruitment in the Musculoskeletal Institute’s Lower Extremity Integrated Practice Unit (IPU), data collection and dissemination via abstracts, presentations and manuscripts for multiple publications. The Fellow will serve as a principal investigator in the lower extremity IPU (2.5 days/week) and supervise student and medical student volunteers in patient recruitment and data collection.
    2. Strategy and Operations: Gain valuable insights into the organization’s strategic planning and clinical/operational needs by attending business and management meetings and becoming involved in operational projects as necessary.
    3. Educational opportunities and networking
      1. Immersion program. The Fellow will participate in our quarterly Musculoskeletal Institute Immersion Program in Value-Based Health Care, which accommodates up to two dozen attendees, including a variety of leading stakeholders in orthopedics and beyond from across the country. The program provides comprehensive insight into our value-based model for musculoskeletal care delivery over two half days of presentations and interactive sessions and ample opportunity for networking and in-depth discussions.
      2. Value-based healthcare curriculum. Complete courses related to Value-Based Health Care through an executive education course from UT Austin’s Value Institute for Health and Care.
      3. AAOS Annual Meeting. The department will support the Fellow’s participation in the AAOS Annual Meeting.
      4. Grand rounds. The Fellow may attend Grand Rounds and other clinical conferences.
    4. Clinical: Exposure to clinical patient care and surgical practices by shadowing faculty in clinical activities (operating room, hospital, and outpatient clinic). Although the Fellow will be most integrated with our Musculoskeletal Institute team, opportunities exist for shadowing and research in other surgical specialties within the Department of Surgery and Perioperative Care, based on the Fellow’s interests. He/she will have ample opportunities to interact with orthopedic surgery residents, as well as other residents and students in the department and throughout Dell Medical School.

    A compensation

    Salary: $35,000 plus benefits. Read more about UT Austin’s employment benefits here.

    Eligibility

    Applicant must have been admitted or enrolled in medical school at the time of application.

    Required: strong critical thinking skills; very motivated; can work well independently and in a team; strong written/verbal communication and organizational skills; basic knowledge of statistics.

    Preferred: Demonstrated interest in value-based healthcare; experience in conducting research projects through publication; completion of core clinical internships (e.g., current third-year medical student); experience creating PowerPoint presentations; skills with data analysis; fluent in Spanish.

    Timeline

    The Fellowship runs from July 1, 2024 to June 30, 2025, although there is some flexibility in dates. The deadline for registration is January 15, 2024. Zoom interviews will be conducted with finalists and we plan to fill the position by March 1stst.

    How to apply

    Submit your resume (with USMLE Step 1 and Step 2 scores, if applicable), a one-page cover letter, and a list of three references via our Workday post. If available, include an example of previous work (PowerPoint presentations, published research, data analysis, etc.).

    If you have any questions about the position or the application process, please contact Lauren Uhler, MPH, Associate Director of Research, at This email address is being protected from spambots. You need JavaScript enabled to view it..

    Learn more

    For more information, visit our website https://dellmed.utexas.edu/education/academics/additional-training-programs/orthopaedic-value-based-health-care-fellowship

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  • You Don’t Look Sick – Living with Rheumatoid Arthritis: DAY 5 HAWAI’I

    I woke up early so I could go to the farmers market. I like looking at the crafts. This time I bought a ring. It is a stainless steel brushed silver ring with very thin rainbow colors along each edge. I had the word ‘resilience’ engraved on it. I like it very much. I also gave my niece a birthday present.

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    Then I went to the Hawaii Tropical Bioreserve and Garden. It is very beautiful. Jungle and flowers and ocean.

    I bought some vegan gelato before heading to an outdoor area with live music and dancing.

    AVvXsEhYkJAtqMRVo dgjH2AL15uAHS9RKn0CsmJHjMF9svMSlP7bwSoFCb3hSWe7Ha o2191n2A2rJTxVwn 7Y2j2CW0MqezMtFzsyximHputFILAvbC7jT j6ybGB1q7Z04K1ervPCGI81oDa3HaWkdi G2pMAZ Xp8aooL2D9m5tfSZahdWTCb2saYFn14

    When I got back to my hotel and opened my door, the hotel cat ran into my room. He wouldn’t leave. I tried to ignore him, use a cord to play with him and feed him. Nothing worked. It took more than an hour before he could leave. I used a paper bag! He wanted to climb in. After I got him out, he climbed onto a table outside my door and tried to knock over a vase. I told him to stop and then he lay down in front of my door and scratched it.

    It was a long night.

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  • RA patients in remission should continue taking TNF inhibitors to prevent flare-ups, the study found

    RA patients in remission should continue taking TNF inhibitors to prevent flare-ups, the study found

    shutterstock 390538711 6b3c40fdd32742caa54307db3553cab1

    New research at ACR Convergence 2023, the annual meeting of the American College of Rheumatology (ACR), found that patients with rheumatoid arthritis (RA) in sustained remission who stopped taking TNF inhibitors (TNFi) had significantly more flares and lower Boolean 2.0 remission rates compared to those who continued treatment. Boolean 2.0 is a revised definition for evaluating disease activity in RA, classifying more patients as achieving remission than Boolean 1.0. It is endorsed by the American College of Rheumatology and the European Alliance for Associations in Rheumatology (EULAR) (Abstract #L07).

    As more RA patients achieve durable remission, questions remain about the long-term effectiveness of tapering and stopping TNFi treatment. In the randomized, multicenter, noninferiority ARCTIC REWIND trial, Siri Lillegraven, MD, MPH, PhD at Diakonhjemmet Hospital, Oslo, Norway, and colleagues compared the three-year effect of tapering versus stable treatment in RA patients in sustained remission. It follows a trial last year.

    The current study included 92 patients from Norwegian rheumatology centers who were randomized 1:1 to taper off TNF inhibitors until discontinuation or continuation of treatment. During the three-year study period, all received study visits every four months. Patients restarted treatment at the full dose if they experienced a flare, which was defined as loss of remission plus an increase in disease activity score of 0.6 units or more and two or more swollen joints. In lieu of these criteria, a doctor and a patient might agree that a significant flare had occurred. The study also looked at remission status, medication use and serious side effects or complications.

    Of the original 92 patients, 80 (87%) completed three-year follow-up. At the end of the study, 75% of patients in the tapering group experienced a flare, compared to 15% in the stable group. Most of those who experienced a flare were in remission by their next office visit (81% in the taper group and 67% in the stable group), although the taper group had significantly lower Boolean 2.0 remission rates throughout the study.

    Lillegraven says the researchers were “somewhat surprised by the difference in the proportion of patients in ACR/EULAR Boolean remission in the two groups,” noting that “although most patients in the taper group experienced a flare within the first year and the earlier resume treatment at full dose Boolean 2.0 remission rates were significantly lower in the tapering TNFi group than in the stable group throughout the study period.”

    The risk difference for flares observed in this data [-24% over three years] is quite similar to what was observed in the one-year study. That’s a bit surprising, because we might have expected that more patients receiving stable treatment would develop a flare over time, narrowing the difference between the two groups.”


    Siri Lillegraven, MD, MPH, PhD at Diakonhjemmet Hospital, Oslo, Norway

    Lillegraven notes that the study’s open-label design could influence the evaluation of flares, but says that study staff “were continuously instructed on the importance of recording flares similarly in both groups, a pragmatic approach that will improve clinical care reflects, where patients know which treatment they are receiving. received.”

    Lillegraven says her team has many studies planned to better understand how to personalize treatment for RA patients in remission. This includes factors that can help determine which patients should and should not taper off their treatment.

    “We have begun planning a 10-year follow-up of the study to better understand the long-term outcomes of different treatment strategies in RA remission. We are [also] consider studies to better understand patient preferences regarding medication tapering.”

    Shared decision-making is central to any consideration of tapering, she says.

    “The patient should be informed of the risks and benefits of tapering, and the patient’s overall situation should be taken into account before the decision is made. Although the data do not support tapering off TNFi at a group level, factors such as side effects related to the treatment or the patient having a strong preference for tapering will obviously influence such a decision.”

    Source:

    American College of Rheumatology

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  • John Booth retires as CEO of Spineology Inc.

    John Booth retires as CEO of Spineology Inc.

    Brian Snider appointed new CEO

    SAINT PAUL, Minn., November 9, 2023–(BUSINESS WIRE)–Spineology Inc. (“Spineology” or the “Company”), the leader in ultra-minimally invasive spine surgery, today announced that John Booth will resign from his position as Chief Executive Officer of Spineology, effective November 10, 2023. The Board of Directors has selected Brian Snider as the next Chief Executive Officer, effective November 13, 2023. Mr. Booth will remain with Spineology through 2024 and serve in an advisory role to enable a smooth transition. Mr. Booth will also resign from the Board of Directors, and the Board of Directors has nominated Mr. Snider as Director.

    Snider joins Spineology with nearly two decades of progressive leadership experience in the medical device industry. Most recently, he served as Executive Vice President of Marketing for Alphatec Spine (NASDAQ: ATEC), as a member of the executive leadership team responsible for growing the company’s market capitalization from $20 million to more than $1.2 billion. During his tenure at ATEC, he was responsible for a variety of marketing and product development disciplines. Most recently he was responsible for the Biologics, Cervical and Thoracolumbar business units. Before joining ATEC, Snider spent nine years at NuVasive, Inc., a leader in innovative products and procedures for minimally disruptive spine surgery. During his tenure at NuVasive, Snider held senior-level marketing roles in the Thoracolumbar business segment, including its flagship procedure, XLIF®. Mr. Snider received his BBA in Marketing and Information Systems from George Washington University and his MBA from the Fuqua School of Business at Duke University.

    “It has been a great privilege to work with a talented and passionate group of employees within the company, who together have significantly advanced the field of ultra-minimally invasive spine surgery over the company’s history,” said John Booth. “I am confident that the company will continue to grow and deliver disruptive solutions under Brian’s leadership as Spineology’s next CEO.”

    Ed Spencer, chairman of the Spineology Board, expressed gratitude for Booth’s leadership. “On behalf of Spineology’s Board of Directors, our employees and shareholders, I express my deep gratitude to John for his success in leading the company, as well as for his service as a member of Spineology’s Board of Directors for more than 20 years .”

    “As we prepared for John’s retirement, the Board unanimously agreed that Brian Snider was well suited to lead Spineology,” Spencer continued. “His years of experience growing evolutionary businesses in the minimally invasive spine market will enable him to immediately contribute to Spineology’s continued success.”

    “I am excited to join the Spineology team,” said Snider. “Spineology is a company with a unique procedural foundation backed by strong clinical data. I am confident that we will achieve growth and surgical advancements in this next phase. I would like to thank the Board of Directors for the opportunity to serve the Spineology team, shareholders and, most importantly, our patients.”

    About Spineology:

    Spineology Inc. is at the forefront of ultra-minimally invasive spine surgery, revolutionizing the way spine surgeons treat and heal back pain. Our patented Mesh technology sets us apart from traditional fusion procedures, allowing surgeons to optimize results while minimizing tissue disruption and improving patient recovery. With a strong commitment to patient-centered care and enabling disruptive technologies, Spineology continues to push the boundaries of what is possible in spine surgery today with the tools of tomorrow.

    Contacts

    Jamison Young
    Finance Director
    651-256-8504
    jyoung@spineology.com

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