GAINESVILLE, Fla., November 1, 2023–(BUSINESS WIRE)–Exactech, a developer and manufacturer of innovative implants, instrumentation and smart technologies for joint replacement surgery, announced the successful first surgery using its new, advanced Activit-E™ polyethylene for the Truliant® Knee Replacement System.
Hany Bedair, MD, performed the procedure at Massachusetts General Hospital (MGH) in Boston, where the material was developed by noted polyethylene expert Orhun Muratoglu, Ph.D., director of the Harris Orthopedic Laboratory at MGH. Dr. Muratoglu was also present at the knee replacement case.
“It’s a profound moment when the inventor who developed our advanced polyethylene is carried into the case at the hospital where it was developed,” said Adam Hayden, CMO and SVP, Large Joints Business Unit at Exactech. “Exactech is extremely proud to offer this next generation of highly cross-linked polyethylene with vitamin E antioxidant.”
Activit-E provides an optimized balance between material strength and toughness through chemically cross-linked polyethylene, while eliminating the need for gamma radiation technology used in previous generations. It provides active oxidative resistance and a long-lasting, high-quality polyethylene bearing, ultimately providing greater strength and active stabilization.
This new generation of polyethylene is the latest, unique innovation from Dr. Muratoglu and his team, including Ebru Oral, Ph.D., director of biomaterials research. Muratoglu invented the first cross-linked polyethylene, and the first of several generations of vitamin E antioxidant polyethylene for leading orthopedic companies.
“It is exciting to perform the first surgical procedure with an implant material both conceived and developed at our hospital,” said Dr. Bedair. “With this advancement, we expect better results compared to knees with traditional, highly cross-linked polyethylene.”
Activit-E recently received 510(k) clearance from the Food and Drug Administration for Exactech knee and ankle replacements. Activit-E will be on display at the 2023 AAHKS Annual Meeting in Dallas, Texas, November 2-5.
References:
Knight, J, Rodgers III, William P, Freedman, Jordan. “Mixed and Hot Irradiated Versus Infused: Mechanical Properties of Vitamin E Cross-linked UHMWPEs.” ORS Annual Meeting 2017. Poster no. 2034.
Muratoglu, O, Asik, M, Nepple, C, Wannomae, K, Micheli, B, Connolly, R, Oral, E. “Dicumyl peroxide cross-linked UHMWPE/vitamin E blend for total joint arthroplasty implants.” Journal of Orthopedic Research. DOI: 10.1002/jor.25679.
About Exactech
Exactech is a global medical device company that develops and markets orthopedic implant devices, related surgical instruments and Active Intelligence® platform of smart technologies for hospitals and doctors. Headquartered in Gainesville, Florida, Exactech markets its products in the United States, in addition to more than 30 markets in Europe, Latin America, Asia and the Pacific. Visit www.exac.com for more information and connect with us on LinkedIn, VuMedi, YouTube, Tweet and Instagram. With Exactech by your side you have EXACTLY what you need.
Contacts
Morgan Lee
Senior Manager Marketing Communications
media@exac.com
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