Author: Mokhtar

Is there a connection between the onset of psoriasis and the risk of autoimmune diseases?

In a recent study published in the Scientific Reports Journal, researchers evaluated the risk of new autoimmune diseases in individuals with early psoriatic disease.

Study: Risk of incident autoimmune diseases in patients with newly diagnosed psoriatic disease: a national population-based study. Image credits: Flystock/Shutterstock.com

Background

Psoriatic disease, which often includes psoriasis and psoriatic arthritis, is a systemic inflammation-related disease with serious clinical consequences.

Autoreactive T lymphocytes, which express proinflammatory cytokines such as interleukins (ILs)-17 and 22, and interferon-gamma (INF-γ) characterize psoriatic diseases.

Studies have linked the autoimmune component of psoriasis to several autoimmune diseases, including autoimmune thyroid diseases, inflammatory bowel disease, alopecia areata, and autoimmune rheumatic diseases.

About the study

In the national population study, researchers evaluated the link between autoimmune diseases and psoriatic diseases.

Patients with newly diagnosed psoriatic disease between January 2007 and December 2019 were included in the study, using the Korean National Health Insurance Service (NHIS) database.

The team used previously established diagnostic algorithms for psoriatic disease in Korea to identify people with the condition. Patients with psoriatic disease had one or more recorded visits with psoriatic diseases such as psoriasis and psoriatic arthritis as their primary diagnostic code and vitamin D prescriptions.

Autoimmune diseases such as CD, UC, Graves’ disease, Hashimoto’s disease, SLE, RA, Sjögren’s syndrome, systemic sclerosis, AS, type 1 diabetes and alopecia areata were studied.

Comparators who had no diagnostic code for psoriatic diseases between January 2005 and December 2019 and no diagnostic code for autoimmune diseases during the washout were randomly selected and matched on sex and age at a 1:1 ratio.

In addition to the diagnostic codes, the researchers also added relevant prescription information for medications and RID codes for all diseases to the diagnostic algorithms for outcomes.

The team added follow-up information on newly identified autoimmune diseases from 2007 to 2020. Multivariate Cox regression modeling was performed to determine adjusted risk ratios (aHRs).

The Charlson Comorbidity Index (CCI) values for comorbidities such as hypertension, diabetes, dyslipidemia, chronic obstructive pulmonary disease (COPD), liver cirrhosis, chronic kidney disease, alcoholic liver disease, and heart failure were determined. The team conducted subgroup analyzes based on gender, age and severity of psoriatic disease.

Patients who received diagnostic codes for psoriatic disease between January 2005 and December 2006 were excluded from the study.

Additionally, the team excluded individuals diagnosed with autoimmune diseases [Crohn’s disease (CD), ulcerative colitis (UC), Graves’ disease, Hashimoto’s disease, systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), Sjögren’s syndrome, ankylosing spondylitis (AS), systemic sclerosis, alopecia areata, and diabetes type 1] before diagnosis of psoriatic disease and those followed for less than one year.

Results

The study included 321,354 individuals in the psoriatic and control groups with a mean age of 43 years, and 59% were men.

Patients with psoriasis showed a significantly increased risk of ankylosing spondylitis, systemic lupus erythematosus, ulcerative colitis, Crohn’s disease, alopecia areata, type 1 diabetes and rheumatoid arthritis, with aHR values of 2.3, 1.9, 1.7 , 2.0, 1.4, 1.2 and 1.6. respectively.

On the other hand, the risks for Hashimoto’s disease, Graves’ disease, systemic sclerosis and Sjögren’s syndrome did not differ significantly between the groups. Type 1 diabetes, alopecia areata, AS, RA, SLE, UC, and CS had NNH values of 9,567, 1,295, 9,946, 3,256, 47,987, 17,899, and 39,988 individual years, respectively.

With the exception of type 1 diabetes, all autoimmune diseases showed a significantly increased risk in psoriatic subjects compared to controls after controlling for CCI and insurance type. After controlling for CCI and insurance type, the risk of type 1 diabetes (aHR, 1.1) was not significant in men with psoriatic disease compared with male controls.

After adjusting for type of insurance and CCI, all autoimmune diseases showed significantly greater risks in younger psoriatic individuals under 40 years of age and in individuals 40 years of age and older compared with controls.

After controlling for insurance type and CCI, CD risk (aHR, 1.4) was not significantly greater in older psoriatic subjects than in controls.

Mild and moderate psoriatic disease occurred in 79% (n=255,285) and 21% (n=66,069) of patients with psoriatic disease, respectively, including the incidence of UC, CD, RA, SLE, alopecia areata, and type diabetes. 1, and AS were greater compared to controls.

After controlling for age, gender, CCI, and insurance type, patients with moderate to severe psoriatic disease showed a significantly increased risk of rheumatoid arthritis, AS, and type 1 diabetes, with aHR values of 1.5, 1.5, and 1.2, respectively.

Conclusion

Based on the study results, patients with psoriatic conditions have a greater chance of developing autoimmune diseases.

This study also found the occurrence of autoimmune diseases unrelated to psoriasis, such as Graves’ disease, Hashimoto’s disease, Sjögren’s syndrome, and systemic sclerosis. Due to the low absolute risk, routine screening for these conditions may not be recommended.

However, appropriate investigations may be necessary in individuals with psoriatic disease to determine the existence of concomitant alopecia areata and provide tailored therapy.

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October 24, 2023
The conversation about weighted vests continues: why we can’t stop raving about weighted vests
By Cameron Vazquez, MPH

We have been here at the Center for Better Bones for many years – and so have our customers! – have sung the praises of weighted training vests and belts. And how can we not do that? Not only does weighted exercise equipment allow us to do less and accomplish more, but numerous studies have shown that weighted vests and belts can improve strength, balance and muscle mass, reduce bone loss and even build bone! You can see all of this research in our blog, Weighing Weight Carrying: How Weighted Vests and Weighted Belts Can Help You. So why are we talking about weighted training equipment again? Because the research in support of weighted vests and belts continues to come to our attention!

The use of weighted vests in a Norwegian clinical trial

Another fascinating study into the impact of weighted training vests on fracture risk factors comes from Norway. (1) This study followed 42 postmenopausal women over 50 years of age with osteopenia and a healed wrist fracture. These participants completed a six-month exercise program called OsteoACTIVE, which consisted of 60-minute sessions held three times a week. The exercises performed were intended for strength, balance, coordination and trunk stabilization. For more details on the exercises performed and to see images, please refer to the original research article.

Weighted vests were used during exercise. Each participant started with two 1.1 kg (about 2.43 pounds) weights, and all but three participants had built up to nine weights (about 21.9 pounds) by the end of the program.

At the end of the six-month program, significant improvement in both hip bone density and quad strength was observed. At the 1-year follow-up, it was discovered that there was a significant improvement in dynamic balance compared to baseline measurements. Here’s another study (2) that confirms these groundbreaking findings on weight-bearing exercise from 1998!

Why we love weighted vests that go beyond their bone benefits

With all the research supporting their positive impact on bone, it’s no wonder we support weighted vests. But the benefits don’t stop there! While it’s incredibly important for your health, we understand that voluntary exercise is no easy feat. With limited time and resources, it’s important to get the most out of your workouts — something that can easily be done with a weighted vest! A few more reasons why we love weighted vests are:
- They are useful: Weighted vests can be worn to add extra weight while doing just about anything, such as household chores, dancing, walking, etc.
- Weight vests involve a progressive program: you can (and should) start slowly and add weight as you go.
- Weighted vests are relatively safe; there is less risk of injury because of the gradual weight gain.
- Weighted vests allow you to do less and achieve more!
We would also like to note that while there isn’t as much research on weighted belts, they are still a good option for many. You can read more about weighted belts in our blog, The Weighted Belt: A New Exercise Tool to Build Bone.

Preventing bone loss during weight loss

Weight loss in overweight adults improves the prognosis of health outcomes; However, such weight loss comes at the expense of the bones. When older adults lose weight, they also lose bone. Currently, American scientists are conducting a study that combines weight loss programs with resistance exercises using the weighted vest. They propose that using weighted vests in combination with resistance exercises will be more effective for preventing weight loss-induced bone loss than resistance exercises alone. (3)

These researchers say that weighted vests are likely to be very useful for several reasons:
- They’re achievable: Older adults are more likely to use a weighted vest than a gym membership, learn about resistance training, or seek good guidance on resistance training.
- Resistance training alone may not be enough to prevent weight loss-related weight loss.
- Weighted vests during exercise can increase BMD and bone turnover and affect muscle strength.
Therefore, the weighted vest could be a solution to prevent unnecessary bone loss during weight loss!

Better sources for bone exercises

Weighted vest and belt

Interested in weighted fitness equipment? You can check out our weighted training vest and belt here!

Webinar with Dr. Belinda Beck from the Australian Bone Clinic

Have you ever been told that as an older person, it’s great to exercise, but exercise won’t build substantial bone strength? Dr. Brown talks to Dr. Belinda Beck, the Australian scientist whose groundbreaking clinical trials clearly demonstrate that older people can rebuild bone mass with high intensity, high resistance and strength training. We like to call her the bone-building mythbuster. Click here to see how Dr. Brown and Dr. Beck discussing exercise and bone health!

Practice evolution with Gina Galli, RYT

Exercise Evolution is our exciting new, affordable subscription program that we offer on Patreon.com. This program includes monthly videos, Dr.’s teaching library. Brown, a community sharing page, monthly exercise plans to build bones, access to the Better Bones Diet, an exercise tracking portal, and more! This program is not only accessible, but also safe. Our goal is to create a community full of like-minded individuals who support each other and are ready to get out there and get healthy!

References:
1. Hakestad, KA, et al. 2015. Exercises including weighted vests and a patient education program for women with osteopenia: a feasibility study of the OsteoACTIVE rehabilitation program. Journal of Orthopedic and Sports Physiotherapy 45(2): 57-147.
2. Shaw, J.M. and C.M. Snow. 1998. Exercise with a weighted vest improves indices of fall risk in older women. The journals of gerontology. Series A, Biological Sciences and Medical Sciences 53(1):M53-M58.
3. Miller, RM, et al. 2021. Integrating nutrition, vesting, education, and strength training (INVEST) into bone health: trial design and methods. Contemporary Clinical Research 104:106326.
I am Dr. Susan E. Brown. I am a clinical nutritionist, medical anthropologist, writer and motivational coach speaker. Learn my proven 6-step natural approach to bone health in my online courses.
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October 24, 2023
Shin Splints Causes, Symptoms and Physical Therapy Treatment
Medial tibial stress syndrome is one of the most common athletic injuries, especially among those who participate in high-impact activities. However, there are other risk factors for shin splints, and not all patients who complain of the characteristic pain along the shin are athletes.

MTSS is a condition that often resolves on its own. Physical therapy can help relieve the pain and prevent it from returning.

What causes shin splints?

There are several muscles in the leg that attach to the shin bone, including the anterior and posterior tibialis muscles, the flexor digitorum longus muscle, and the soleus muscle. These muscles and their connective tissue can pull on the periosteum, a layer of tissue that covers the bone and allows the muscles to attach.

Repeated stress can cause the periosteum to become inflamed, resulting in the pain of shin splints. There are several risk factors that can contribute to MTSS.

1. Physical activity

Athletes who do a lot of running and jumping, such as gymnasts, basketball players, dancers, tennis players and sprinters, are at particular risk for shin splints. An estimated 35% of these athletes eventually develop MTSS.

Due to frequent marching and other physically demanding tasks, soldiers are at risk of developing shin splints, with a incidence rate that can be as high as 35%.

2. Weak bones

MTSS may be more likely in people with underlying medical conditions that weaken the bones, such as osteoporosis or osteopenia. Other underlying medical conditions that can affect bone health and increase the risk of shin splints include eating disorders, vitamin D deficiencies, or hormonal changes in women that can also result in a loss of normal menstruation.

3. Flat feet

Overpronation occurs when the arch of the foot collapses due to the impact of a step. This is colloquially known as having flat feet. If you often walk or run with flat feet, this can strain the tibial periosteum and lead to shin splints. You can also develop MTSS if your arches are stiff or high. Exercising or playing sports in shoes that do not provide adequate arch support can contribute to overpronation and increase the risk of shin splints.

4. Overweight

Carrying extra weight puts more strain on the lower extremities and increases the risk of shin splints. Maintaining a healthy weight is important for shin splint prevention and overall health, but you should begin an exercise program gradually. Demanding too much of the body at once can also contribute to shin splints.

How can shin splints be prevented?

Chances are you will develop MTSS at the start of your athletic season or a new training regimen. In your eagerness to get started, you may try to do too much too quickly, putting too much pressure on your lower legs.

Starting with a gentle exercise program and progressing slowly is therefore important to prevent shin splints. Limiting activity increases to 10% per week helps prevent sudden changes that can trigger MTSS.

If your muscles are not properly warmed up before physical activity, they can put pressure on your shin. Be sure to stretch your entire body, especially your legs, before beginning any exercise or athletic event.

Supportive footwear helps prevent overpronation, so be sure to replace the shoes you use for exercise before they wear out. If you are a runner, replace your running shoes every 300 miles. If your shoes do not provide enough support, you can use arch supports that are specially designed to prevent overpronation.

Try cross-training with low-impact exercises, such as cycling or swimming, to give your lower legs a chance to rest and recover. When participating in high-impact activities, try to avoid uneven, hilly terrain and hard surfaces.

How can physical therapy help treat shin splints?

The prognosis for shin splints is usually very good and most people recover completely. The key is to relieve pressure on the inflamed tissues so they have a chance to heal. There are several physiotherapy techniques that can help relieve stress in the superficial tissues:
- Foam rolling
- Massage
- Tool-assisted therapy
If the tension is in the deeper tissues of the muscle, these techniques may not be enough to relieve it. However, trigger point dry needling is another technique that can reach beyond the superficial tissues to relieve tension in the fibers in the muscle belly. The goal is for the muscle fibers that are better equipped for the task to absorb the stress instead of the periosteum.

In addition to helping relieve the pain of MTSS, physical therapy can also help prevent symptoms from coming back. You can learn exercises to prevent overpronation by strengthening the arch of your foot. Although it may seem counterintuitive at first, strengthening the muscles that control hip movement can help reduce tension in the lower leg.

Your physical therapist may also suggest shoes that provide better support and adjustments to your activities to reduce stress on your lower leg and prevent shin splints from coming back.

As you progress through therapy and eventually return to your previous activities, use pain as a guide and stop when it starts to hurt. Trying to push through the pain of shin splints only makes the problem worse. make an appointment today with a Foothills physical therapist.
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October 24, 2023
Celebrating Patient Recognition Week: the importance of keeping your bones and joints healthy

February 1 marks the start of Patient Recognition Week, an annual event celebrating the important role of patients in the healthcare system. As the name suggests, this week is all about recognizing and honoring the hardworking patients who place their trust in the hands of medical professionals. But it’s not just about celebrating patients; it is also about promoting good health and well-being.

Caring for our bones and joints is one of the most important aspects of maintaining good health. Our bones and joints play a crucial role in our daily lives, allowing us to move, work and play. Without healthy bones and joints, we wouldn’t be able to perform even the most basic tasks. That’s why it’s so important to take care of these vital parts of our body.

What can we do to keep our bones and joints healthy? Here are a few tips:

Exercise regularly to keep your bones and joints strong

Exercise is one of the best things you can do to keep your bones and joints healthy. Regular exercise helps strengthen bones and improve joint flexibility.

It’s important to find an exercise routine that you enjoy, whether it’s running, swimming or yoga. The key is to make sure you get at least 30 minutes of moderate-intensity exercise every day.

Eat a healthy, balanced diet to support your bones and joints

A healthy diet is essential for maintaining strong bones and joints. Calcium and vitamin D are crucial for bone health, so include plenty of dairy products, green leafy vegetables and oily fish in your diet. Getting enough protein is also vital as it helps repair and build body tissues.

Don’t ignore pain or discomfort in your bones and joints

If you experience pain or discomfort in your bones or joints, it is essential to seek medical attention. Ignoring these symptoms can lead to further problems down the road.

At Bone & Joint Specialists Orthopedic Center of Indiana, our team of experienced orthopedic specialists are ready to help you with all your orthopedic needs.

Contact us at 219-795-3360 to schedule an appointment or ask questions about your orthopedic concerns.

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October 24, 2023
Curovate is a physical therapy app for knee replacement, ACL and more

Document

I started my company, Curovate, with a very simple vision, to make physiotherapy accessible to everyone worldwide. That was in 2015. Our physiotherapy app Curovate was originally released on the Google Play Store on August 1, 2016. When we first released the app, it provided rehabilitation for people after anterior cruciate ligament (ACL) surgery. Seven years later, Curovate provides rehabilitation for all of the following physiotherapy-related issues on both iOS and Android devices:

The video below gives a short preview of everything Curovate can help you with in your daily rehabilitation. The main purpose of our physiotherapy app is to help you stay consistent with your daily rehabilitation exercises at home after an injury or surgery.

Curovate is a physiotherapy app for recovery before or after knee replacement, ACL surgery, knee osteoarthritis, knee strengthening exercises, hip strengthening exercises or hip replacement. Curovate has been developed and supported by physiotherapists.

To learn more about our app and how it can help you with your recovery, visit our website here. Or download Curovate from the links below and get started on your recovery!

If you need more tailored help during your surgery or recovery from your injury, check out our Virtual Physiotherapy page to book your 1-on-1 video session with a physiotherapist.

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October 24, 2023
Fostering intimacy while living with an illness or disability

Although chronic diseases are quite common (the Centers for Disease Control and Prevention says that 6 in 10 adults in the US have one chronic disease, and 4 in 10 have two or more chronic diseases), I’ve always had trouble finding tools that address the impact that chronic illness can have on relationships and intimacy.

Now there’s a book that addresses exactly that problem: Sex – Interrupted: Fostering Intimacy While Living with Illness or Disability. Iris Zink, rheumatology nurse, and Jenny Thorn Palter, former editor of Lupus now magazine, have written a book that recognizes the intimacy issues that patients with chronic diseases often face and offers helpful suggestions for both healthcare providers and patients.

Click below to read my review of the book!

Book review: Sex – Interrupted: Fostering Intimacy While Living with Illness or Disability

Moms facing forward

You can also visit www.intimacyandillness.com For more information. The first 50 people to purchase the book through their website will receive a free sample copy of Pure Romance.

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October 24, 2023
Plums for your bones – Food for healthy bones
Eating plums for your bones can help prevent or slow bone loss by reducing inflammation and oxidative stress. There are two delicious recipes on my plum blog.

Skelly and I spend a lot of time promoting strong bones and how to nourish them. But many women we meet don’t think about it – until it’s too late.

Some women are so concerned about preventing cancer and heart disease that they don’t bother to worry about their bones. But the thing is: as a woman, you have a 50/50 chance of breaking a bone as you get older. Those are pretty bad odds.

Broken bones are even more common in women than heart attack, stroke and breast cancer combined. [1]

And supporting your bones is easier than you think. You can do something good for your bones with every meal.

Let me give you just one example of powerful bone food...

I’m talking about plums

Or as some people like to say, ‘dried plums’.

As we age, lower estrogen levels can lead to inflammation and oxidative stress. These can increase bone loss and fractures.

Plums rich in minerals

Vitamin K, phenolic compounds and dietary fiber. These can all combat oxidative stress and inflammation.

The evidence was recently published in the journal Advances in nutrition. [2]

Researchers looked at 28 studies in both humans and animals. They found that women who ate about ten plums a day for a year improved bone mineral density in the forearm and lower back. They also found that eating just 5 to 10 plums per day for six months prevented loss of bone mineral density and reduced bone resorption.

Plums help reduce bone loss because they are high in polyphenols. These are powerful antioxidants. Other fruits are also rich in polyphenols, including apples, blackberries, cherries, grapes, pears, pomegranates, raspberries and strawberries. [3]

More antioxidants than any other fruit

Plums also give you a boost of a little-known bone mineral called drill. It ensures that bones do not lose calcium and magnesium. It also helps your body produce and use vitamin D, which is crucial for bone formation.

And of course, prunes have additional benefits for your colon and help you stay regular. Studies show they improve your gut microbiota (bacteria) and may help reduce your risk of colon cancer.[4]

Low glycemic index

If you’re worried about getting too much sugar from dried fruit, plums are still a good choice. One serving of about 60 grams or 6 plums is only 29 on the glycemic index. [5]

Everything below 55 is considered low. That means they won’t give you a sugar rush thanks to their high fiber content. Just make sure that the plums you buy do not contain added sugars.

Skelly and I are always looking for easy ways to sneak a little spice into our day. We like to chop up a few plums and throw them on our morning oatmeal. You can also add them to a healthy green smoothie (make sure these are pitted plums) or to your yogurt. Or just grab a few for an on-the-go snack.

Osteoblasts – Bone building cell

Last: “Animal and cell studies suggest that prunes and/or their extracts improve bone formation and inhibit bone resorption through their action on cell signaling pathways that influence the differentiation of osteoblasts and osteoclasts.” [6]

From my bones to yours,

Irma Jennings INHC,

Your holistic bot coach

^[1] JA Cauley et al. “Incidence of Fractures Compared with Cardiovascular Disease and Breast Cancer: The Women’s Health Initiative Observational Study” Osteoporosis Int. 2008; 19(12): 1717–1723.

^{^[2]} Janhavi et al., “The Role of Plums in Modulating Inflammatory Pathways to Improve Bone Health in Postmenopausal Women,” Advances in nutrition, 2022; nmab162, https://doi.org/10.1093/advances/nmab162

^{^[3]} Jonny Bowden, “The 150 Healthiest Foods in the World, Revised Edition: The Surprising, Unbiased Truth About What You Should Be Eating and Why.”

^[4] Texas A&M AgriLife. “Plum good health benefits.” ScienceDaily. www.sciencedaily.com/releases/2015/09/150927120304.htm (accessed February 23, 2022).

^[5] What is the glycemic index of plums? https://www.livestrong.com/article/415499-glycemic-index-of-prunes/ (accessed February 25, 2021).

[6] https://pubmed.ncbi.nlm.nih.gov/28422064/

Want more bone-loving recipes?

Below is the link to purchase mine downloadable guide:

7 Day Meal Plan – Simple Cooking for Bone Health

With 27 bone-loving recipes, shopping lists, nutrition plan, storage tips, weekly tips and much more.

A fully clickable download guide to help you navigate through the recipes and all the information in this manual.

The best $47 dollars you can spend on your bot.

Below, my team created two plum recipes:

1 for vegetarians/vegans and the other for animal protein eaters.

I would appreciate giving these recipes a vote just below the description.
Tempting Tempeh with Plums

Plums can help you prevent or delay bone loss. As we age, lower estrogen levels can lead to inflammation and oxidative stress. These can increase bone loss and fractures. Plums are rich in minerals, vitamin K, phenolic compounds and dietary fiber. These can all combat oxidative stress and inflammation.

Find more bone-loving recipes on my Comprehension Bone Health Program (CBHP) waiting list here!

View all recipes here.

Preparation time 2 o’clock 30 minutes

Cooking time 20 minutes

Total time 50 minutes

Class Main dish

kitchen American

Portions 4

Calories 119 kcal

2 – 8 Oz Tempeh organic packages

Marinade

1 cup water

8 plums

1/4 cup syrup Black belt

2 Tablespoon apple cider vinegar

1 Tablespoon Dijon mustard

3 clove garlic minced meat

1 teaspoon thyme dry

1/2 teaspoon ginger ground

1/2 teaspoon turmeric

1 teaspoon sea salt

Make the marinade by combining the water, molasses, prunes, vinegar, mustard, garlic and spices in a high-speed blender.

Marinate the tempeh in the refrigerator for at least 2 hours or overnight.

Preheat the oven to 400 degrees F.

Place the marinated tempeh in a glass baking dish.

Bake at 400 degrees F for 15-20 minutes

Cook once – eat twice

The nutritional information is calculated automatically and may vary based on the ingredients and products used.

Calories: 119kcalCarbohydrates: 30GEgg white: 23GFat: 1GSaturated fat: 1GPolyunsaturated fat: 1GMonounsaturated fat: 1GSodium: 636mgPotassium: 487mgFiber: 2GSugar: 23GVitamin A: 183IUVitamin C: 2mgVitamin K: 12µgCalcium: 64mgIron: 1mgMagnesium: 64mgPhosphorus: 31mgSelenium: 5µgZinc: 1mg

Keyword Gluten-free, osteopenia, osteoporosis, vegan, vegetarian
Powerful pork chops with plums

Plums can help you prevent or delay bone loss. As we age, lower estrogen levels can lead to inflammation and oxidative stress. These can increase bone loss and fractures. Plums are rich in minerals, vitamin K, phenolic compounds and dietary fiber. These can all combat oxidative stress and inflammation.

Find more bone-loving recipes on my Comprehension Bone Health Program (CBHP) waiting list here!

View all recipes here.

Preparation time 2 o’clock 30 minutes

Cooking time 15 minutes

Total time 45 minutes

Class Dinner, main course

kitchen American

Portions 4

Calories 326 kcal

1 Frying pan

1 Meat thermometer

1 covered bowl

4 pork chops Bone-in pork tenderloins, about 6 oz each

Marinade

1 cup water

8 plums coarsely chopped

1/4 cup syrup

2 Tablespoon apple cider vinegar

1 Tablespoon Dijon mustard

3 clove garlic minced meat

1 teaspoon sea salt

1/2 teaspoon black pepper ground

1 teaspoon thyme dry

1/2 teaspoon ginger ground

1/2 teaspoon turmeric

Marinade

Using a high-speed blender, combine the water, molasses, prunes, vinegar, mustard, garlic and spices.

Pork chops

Marinate the chops in a covered container in the refrigerator for at least 2 hours or overnight.

Preheat the oven to 400 degrees F.

Remove the pork from the marinade.

Heat a frying pan until hot.

Place the pork chops in the pan and sear on one side for 3-4 minutes.

Place the skillet in the oven and bake.

Chops are ready when a meat thermometer registers 140-145 degrees F.

Start checking the meat after 6 minutes – check again every minute (best to use the thermometer on the side of the chop).

Extra marinade: bring to a low boil, reduce and use as a dressing over the pork.

Cook once – eat twice

The nutritional information is calculated automatically and may vary based on the ingredients and products used.

Calories: 326kcalCarbohydrates: 30GEgg white: 30GFat: 10GSaturated fat: 3GPolyunsaturated fat: 1GMonounsaturated fat: 4GTrans fat: 1GCholesterol: 90mgSodium: 700mgPotassium: 988mgFiber: 2GSugar: 23GVitamin A: 190IUVitamin C: 2mgVitamin D: 1µgVitamin K: 12µgCalcium: 74mgIron: 2mgMagnesium: 99mgPhosphorus: 333mgSelenium: 50µgZinc: 2mg

Keyword Gluten free, osteopenia, osteoporosis, pork chops, prunes
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October 24, 2023
Aurora Spine announces the closure of private placement financing

Carlsbad, California, October 23, 2023 (GLOBE NEWSWIRE) — Aurora Spine Corporation (“Aurora Spine” or the “Company”) (TSX VENTURE: ASG) (OTCQB: ASAPF) is pleased to announce that it has completed a non-brokered private placement of units (“Units”) at gross proceeds of approximately CDN$1.9 million (the “Offering”).

As a result of the Offering, the Company issued 6,445,939 Units at a price of CDN$0.30 per Unit. Each Unit consists of one common share of the Company and one warrant to purchase common shares of the Company. Each whole warrant is exercisable at a price of CDN$0.50 per common share for a period of 24 months from the date of issuance. In connection with the Offering, the Company paid finders’ fees in the aggregate amount of CDN$50,700. PowerOne Capital Markets Limited acted as finder in connection with a portion of the Offering.

The Company intends to use the proceeds from the Offering to finance increased working capital resulting from expected growth in sales of several of its new products, including SiLO TFX and Dexa/Apollo, and from ZIP’s continued growth as Aurora adds new direct sales staff.

The securities issued under the Offering will be subject to a four-month hold period in accordance with applicable securities laws. The Offering is subject to final approval by the TSX Venture Exchange.

Certain directors of the Company (collectively the “Insiders”) participated in the Offering and as such the Offering may constitute a related party transaction under Multilateral Instrument 61-101 – Protection of Minority Security Holders in Special Transactions (“MI 61-101”) , but is otherwise exempt from the formal minority interest valuation and approval requirements of MI 61-101 under sections 5.5(a) and 5.7(1)(a) of MI 61-101 with respect to such Insider participation in the Offer . No special committee has been established in connection with the Offering or the Insiders’ participation in the Offering, and no material contrary position has been expressed or abstained from by any director of the Company in connection therewith. Further details will be included in a material changes report to be submitted by the Company in connection with the completion of the Offering. The Company filed the material change report no more than 21 days prior to the initial closing date of the Offering as the terms of the Offering and the total amount to be invested by the Insiders were only settled shortly before the closing of the Offering. and the Company wished to complete the Offering on an accelerated basis for sound business reasons.

This press release does not constitute an offer to sell or the solicitation of an offer to buy securities in the United States. The securities have not been and will not be registered under the United States Securities Act of 1933, as amended (the “US Securities Act”) or any state securities laws, and may not be offered or sold within the United States or to US persons, unless registered under the United States Securities Act and applicable state securities laws or an exemption from such registration is available.

About Aurora Spine

Aurora Spine focuses on bringing new solutions to the spine implant market through a range of innovative, minimally invasive, regenerative spine implant technologies. Additional information can be found at www.aurora-spine.com or www.aurorapaincare.com.

Forward-Looking Statements

This press release contains forward-looking information that involves substantial known and unknown risks and uncertainties, most of which are beyond Aurora Spine’s control, including, without limitation, those set forth under “Risk factors” And “Cautionary Note Regarding Forward-Looking Information” in Aurora Spine’s final prospectus (collectively, “forward-looking information”). Forward-looking information in this press release includes information regarding the Offering, the completion of the Offering and the approval of the Offering by the TSX Venture Exchange. Aurora Spine cautions investors in the securities of Aurora Spine of important factors that could cause Aurora Spine’s actual results to differ materially from those projected in the forward-looking statements contained in this press release. Any statements that express or imply expectations, beliefs, plans, objectives, assumptions or future events or performance are not historical facts and may be forward-looking and may involve estimates, assumptions and uncertainties that could cause actual results or outcomes. to differ unilaterally from the statements expressed in such forward-looking statements. There can be no assurance that the expectations set forth herein will prove to be correct and, accordingly, potential investors should not place undue reliance on these forward-looking statements. These statements speak only as of the date of this press release.

For more information please contact:

Aurora Spine Corporation

Trent Northcutt
president and director
(760) 424-2004

Chad Clouse
Finance Director
(760) 424-2004

www.aurora-spine.com

Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

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October 24, 2023
August 2023 Schedule — Bone Talk
Bone Buddies Virtual Support Group: August 2023 schedule

Join the Bone Buddies Online Virtual Support Group this August! Weekly sessions cover topics ranging from diet, exercise, treatment and more!
- Wednesday, August 9 at 5:30 PM CDT: Free practice session
- Saturday, August 12 at 10am CDT: Presentation on Genetic Influences on Low Bone Density
- Thursday, August 17 at 2:00 PM CDT: August Healthy Eating Session
- Saturday, August 19: Practice session at 10am CDT; then 11am CDT review of the presentation on Genetic Influences on Low Bone Density
- Wednesday, August 23 at 5:30 PM CDT: Review of the presentation on Genetic Influences on Low Bone Density
- Saturday, August 26: Practice session at 10am CDT; then at 11am CDT Open Forum/Best Practices
If you would like to join one of the sessions, please email Elaine Henderson at eshenderson214@gmail.com for the Zoom links. Feel free to share the meeting information with others who may be interested in attending!

About Bone Buddies

The Bone Buddies virtual online support group is open to everyone and typically meets on the second Saturday of every month at 10 a.m. Central Time on Zoom. On weeks when there is no support group meeting, the group usually meets on Zoom on all other Saturdays at 10 a.m. Central Time for free practice sessions.

A discussion about healthy eating also takes place every third Thursday at 2:00 PM Central Time on Zoom. You can submit questions to a registered dietitian. She will then receive an overview of the questions. She will also answer your questions if you attend the meeting.

Group meetings are a fun, relaxing way to learn new information about bone health and managing osteoporosis. It can also be a great way to meet others dealing with low bone density.

Send an email to Elaine Henderson at eshenderson214@gmail.com for the Zoom links. Feel free to share the meeting information with others who may be interested in attending!
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October 24, 2023
College athletes experience worse outcomes after injury due to concussions suffered outside of sport

Researchers at the Children’s Hospital of Philadelphia (CHOP) found that college athletes had worse outcomes after injury due to concussions suffered outside of sports than those they experienced while playing sports. In addition, female athletes who sustained their injuries outside of exercise had more severe symptoms and more sports days lost due to injuries than male athletes. These findings suggest the need for improved recognition, reporting, and monitoring of concussions outside of sport.

The study was recently published online by the Journal of Athletic Training.

Concussions can affect the daily functioning and quality of life of those who sustain them. Prompt recognition of symptoms and early access to care can help minimize these effects. Most concussion research has focused primarily on injuries that occur during sports, but those studies often exclude concussions that can occur outside of sports, usually due to falls or car accidents. Some studies have shown that patients with non-sports-related concussions have worse outcomes, but research on these effects in college-age patients is very limited.

“Patients who experience a concussion outside of sport may lack the resources that athletes who sustain their injury on the field have for concussion care, such as immediate access to health care providers such as athletic trainers,” said first author Patricia Roby, PhD, one of the researchers. injury scientist who conducted this study while she was a postdoctoral researcher at CHOP.

To help address this gap in knowledge, researchers analyzed data from the National Collegiate Athletic Association-Department of Defense Concussion Assessment, Research, and Education (CARE) Consortium. A total of 3,500 college athletes participated in the study, including 555 who had suffered a non-sports-related concussion. More than 40% of participating athletes were female, allowing potential differences in recovery between men and women to be explored.

The study found that athletes who had suffered non-sports related concussions were less likely to report their injuries immediately, possibly due to a lack of recognition of the symptoms outside the sporting environment or a hesitation to report the injury caused by unusual or careless mechanisms . Athletes who suffered non-sports-related concussions reported greater severity of their symptoms, more days with symptoms, and more days of sport lost due to injuries compared to patients who suffered sport-related concussions, and these findings were even more true in female patients compared with male patients.

“Our findings demonstrate that non-athletic mechanisms of concussion injury are an important consideration in college-age young adults, something we had already described in our study in younger children. There is an opportunity to improve clinical outcomes by raising awareness and increasing concussion education. That happens outside of sports and also reduces barriers to healthcare reporting in this older age group,” said senior study author Christina L. Master, MD, clinical director of the Minds Matter Concussion Program at CHOP. “Additionally, our findings regarding gender differences in the trajectory of these injuries require additional research to see the extent to which reporting behavior and access to medical teams contribute to this disparity in outcomes.”

This study was supported by the National Institute of Neurologic Disorders and Stroke of the National Institutes of Health, grants R01NS097549 and T32NS043126, and the Grand Alliance Concussion Assessment, Research, and Education (CARE) Consortium, funded in part by the National Collegiate Athletic Association. NCAA) and the Department of Defense (DOD). This work was also supported by the Office of the Assistant Secretary of Defense for Public Health Affairs, through the Combat Casualty Care Research Program, endorsed by the Department of Defense, through the Joint Program Committee 6/Combat Casualty Care Research Program – Psychological Health and Program for traumatic brain injury under award number W81XWH1420151.

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October 24, 2023